A Randomized, Double-Blind, Trial Comparing Epinephrine Versus Phenylephrine as a Vasoconstrictor in Regional Anesthesia for Upper Extremity Surgery

This study has been completed.
Sponsor:
Information provided by:
New York Methodist Hospital
ClinicalTrials.gov Identifier:
NCT00225043
First received: September 21, 2005
Last updated: May 30, 2008
Last verified: May 2008
  Purpose

The study involves research, the purpose of which is to compare three different drug mixtures (Epinephrine, Phenylephrine 25 µg, or Phenylephrine 50 µg). Specifically, how long each medicine lasts will be studied.


Condition Intervention
Healthy
Drug: Epinephrine/phenylephrine

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind

Resource links provided by NLM:


Further study details as provided by New York Methodist Hospital:

Enrollment: 60
Study Start Date: June 2005
Study Completion Date: August 2007
Primary Completion Date: August 2007 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Shoulder surgery with regional anesthesia

Exclusion Criteria:

  • Shoulder surgery with general anesthesia unhealthy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00225043

Locations
United States, New York
New York Methodist Hospital
Brooklyn, New York, United States, 11215
Sponsors and Collaborators
New York Methodist Hospital
Investigators
Principal Investigator: Joel Yarmush, MD, MPA New York Methodist Hospital
  More Information

No publications provided

Responsible Party: Joel Yarmush, New York Methodist Hospital
ClinicalTrials.gov Identifier: NCT00225043     History of Changes
Other Study ID Numbers: 299
Study First Received: September 21, 2005
Last Updated: May 30, 2008
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Epinephrine
Racepinephrine
Phenylephrine
Oxymetazoline
Epinephryl borate
Adrenergic alpha-Agonists
Adrenergic Agonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Physiological Effects of Drugs
Adrenergic beta-Agonists
Bronchodilator Agents
Autonomic Agents
Peripheral Nervous System Agents
Anti-Asthmatic Agents
Respiratory System Agents
Therapeutic Uses
Mydriatics
Sympathomimetics
Vasoconstrictor Agents
Cardiovascular Agents
Cardiotonic Agents
Nasal Decongestants
Adrenergic alpha-1 Receptor Agonists
Protective Agents

ClinicalTrials.gov processed this record on September 18, 2014