Cytodiagnosis of Basal Cell Carcinoma and Actinic Keratosis Using Papanicolaou and May-grunwald-giemsa Stained Tissue Smear

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:
NCT00218868
First received: September 20, 2005
Last updated: February 9, 2012
Last verified: February 2012
  Purpose

The purpose of this study is to compare and evaluate the diagnostic performance of scrape cytology using two different cytological staining techniques, and to evaluate additional touch imprint cytology with that of histopathology of superficial basal cell carcinoma and actinic keratosis.


Condition Intervention
Carcinoma, Basal Cell
Porokeratosis, Disseminated Superficial Actinic
Procedure: Skin scrape

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cytodiagnosis of Basal Cell Carcinoma and Actinic Keratosis Using Papanicolaou and May-grunvald-giemsa Stained Cutaneous Tissue Smear in Relation to Photodynamic Therapy

Resource links provided by NLM:


Further study details as provided by Norwegian University of Science and Technology:

Enrollment: 66
Study Start Date: January 2000
Study Completion Date: November 2007
Primary Completion Date: February 2006 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
skin scrape Procedure: Skin scrape
scrape cytology using two different cytological staining techniques, and additional touch imprint cytology compared with histopathology of superficial basal cell carcinoma and actinic keratosis

  Eligibility

Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

50 BCC and 28 AK histologically verified lesions, from 41 and 25 patients, respectively

Criteria

Inclusion Criteria:

Histologically verified basal call carcinoma and actinic keratosis

Exclusion Criteria:

Morphea form of basal cell carcinoma. Pigmented form of basal cell carcinoma.

  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00218868

Locations
Norway
St. Olav University Hospital
Trondheim, Norway, 7006
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
Principal Investigator: Eidi Christensen, MD St. Olav, University Hospital, Trondheim
  More Information

Publications:
Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00218868     History of Changes
Other Study ID Numbers: EC-001
Study First Received: September 20, 2005
Last Updated: February 9, 2012
Health Authority: Norway:National Committee for Medical and Health Research Ethics

Keywords provided by Norwegian University of Science and Technology:
Cytodiagnosis
Skin Scrape
Touch Imprint
Papanicolaou
May-Grunvald-Giemsa

Additional relevant MeSH terms:
Carcinoma
Carcinoma, Basal Cell
Keratosis
Keratosis, Actinic
Porokeratosis
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Basal Cell
Skin Diseases
Precancerous Conditions
Skin Diseases, Genetic
Genetic Diseases, Inborn

ClinicalTrials.gov processed this record on September 18, 2014