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| Sponsor: | Institut de Recherches Cliniques de Montreal |
|---|---|
| Information provided by: | Institut de Recherches Cliniques de Montreal |
| ClinicalTrials.gov Identifier: | NCT00208221 |
Purpose
The purpose of this study is to determine if a dose of ramipril combined with a normal dose of telmisartan 80 mg will be more effective than ramipril 20 mg in reducing microalbuminuria in hypertensive patients with diabetes.
| Condition | Intervention | Phase |
|---|---|---|
|
Hypertension Type 2 Diabetes Albuminuria |
Drug: ramipril Drug: ramipril-telmisartan |
Phase III |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study |
| Official Title: | Comparison of a Higher Dose of Ramipril to the Addition of Telmisartan 80 mg+Ramipril 10 mg in Patients With Hypertension and Diabetes |
| Estimated Enrollment: | 50 |
| Study Start Date: | August 2006 |
| Study Completion Date: | June 2007 |
The purpose of this study is to determine the effects of ramipril 10 mg and telmisartan 80 mg versus ramipril 20 mg in patients with diabetes type II, hypertension and microalbuminuria (Urinary-albuminuria creatinine ratio of 2.0 to 25 mg/mmol) on
Eligibility| Ages Eligible for Study: | 18 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Canada, Quebec | |
| Institut de Recherches Cliniques de Montreal | |
| Montreal, Quebec, Canada, J4X 1J3 | |
| Principal Investigator: | Pierre Larochelle, MD PhD FRCPC | Institut de Recherches Cliniques de Montreal |
More Information
| Study ID Numbers: | RD 0507/17259 |
| Study First Received: | September 13, 2005 |
| Last Updated: | November 7, 2007 |
| ClinicalTrials.gov Identifier: | NCT00208221 History of Changes |
| Health Authority: | Canada: Health Canada |
|
Hypertension Diabetes Microalbuminuria Blood pressure |
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Molecular Mechanisms of Pharmacological Action Ramipril Signs and Symptoms Urologic Diseases Therapeutic Uses Angiotensin-Converting Enzyme Inhibitors Cardiovascular Diseases Telmisartan Metabolic Diseases Albuminuria Urination Disorders Vascular Diseases Diabetes Mellitus |
Endocrine System Diseases Enzyme Inhibitors Cardiovascular Agents Antihypertensive Agents Pharmacologic Actions Protease Inhibitors Angiotensin II Type 1 Receptor Blockers Urological Manifestations Proteinuria Diabetes Mellitus, Type 2 Glucose Metabolism Disorders Hypertension |