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Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

This study is currently recruiting participants.
Verified by University Hospital, Limoges, September 2005

Sponsored by: University Hospital, Limoges
Information provided by: University Hospital, Limoges
ClinicalTrials.gov Identifier: NCT00199628
  Purpose

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.


Condition
Glomerulonephritis, Membranous
Neonatal Diseases and Abnormalities
Hemochromatosis

Genetics Home Reference related topics:   hemochromatosis   

MedlinePlus related topics:   Hemochromatosis   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Longitudinal, Defined Population, Prospective Study
Official Title:   Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Further study details as provided by University Hospital, Limoges:

Estimated Enrollment:   100
Study Start Date:   September 2005

  Eligibility
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Criteria

Inclusion Criteria:

Mothers having a child suffering from:

  • Neonatal membranous glomerulonephritis
  • Unexplained neonatal tubular defect
  • Unexplained thrombotic microangiopathy
  • Neonatal hemochromatosis

Exclusion Criteria:

  • Any cause explaining the child's disease
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00199628

Contacts
Contact: Vincent Guigonis, MD     +33(0)555 056 358     vincent.guigonis@chu-limoges.fr    

Locations
France
Limoges University Hospital     Recruiting
      Limoges, France, 87042
      Contact: Vincent Guigonis, MD     +33(0) 555 056 358     vincent.guigonis@chu-limoges.fr    
      Principal Investigator: Vincent Guigonis, MD            

Sponsors and Collaborators
University Hospital, Limoges

Investigators
Principal Investigator:     Vincent Guigonis, MD     Department of Pediatrics, Limoges University Hospital    
  More Information


Study ID Numbers:   I05001
First Received:   September 14, 2005
Last Updated:   March 10, 2006
ClinicalTrials.gov Identifier:   NCT00199628
Health Authority:   France: Ministry of Health

Keywords provided by University Hospital, Limoges:
fetomaternal tissular alloimmunization  
Mothers having a child suffering from:  
neonatal membranous glomerulonephritis  
unexplained neonatal tubular defect
unexplained thrombotic microangiopathy
neonatal hemochromatosis

Study placed in the following topic categories:
Glomerulonephritis
Autoimmune Diseases
Metabolic Diseases
Hemochromatosis, type 3
Glomerulonephritis, Membranous
Iron Metabolism Disorders
Metabolism, Inborn Errors
Urologic Diseases
Genetic Diseases, Inborn
Nephritis
Hemochromatosis
Infant, Newborn, Diseases
Kidney Diseases
Iron Overload
Metabolic disorder
Congenital Abnormalities

Additional relevant MeSH terms:
Immune System Diseases
Metal Metabolism, Inborn Errors

ClinicalTrials.gov processed this record on October 15, 2008




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