Researchers frequently need tissue samples (blood, urine, saliva, sweat, or other body fluid/tissue) to help them understand more about a particular disease or process. This protocol is designed to create the opportunity to obtain such samples that would otherwise be discarded during the course of usual clinical care, or alternatively to obtain such samples during patient screening for other studies.

Community

Inclusion Criteria:

• 18 years of age or older
• Identified by the investigator to have a condition of interest (cardiovascular disease, cancer, endocrine disease, neurological disease, arthritis, psychiatric disease) for exploratory studies related to the patient's illness or other feature that offers the possibility of generation of hypotheses for future studies

Exclusion Criteria:

• Unwilling to be subjected to diagnostic and/or therapeutic procedures that are not necessary for clinical management
• Excessive blood loss in this study plus other research participation and/or clinical evaluation that will result in blood loss of greater than 1 unit (400ml or 1 pint) over an 8 week period
• Inability to give informed consent