Intravenous-Morphine and Glucagon-Usage Enhanced MR Cholangiography

This study is currently recruiting participants.

Verified by National Taiwan University Hospital, April 2005

First Received: September 8, 2005 Last Updated: November 25, 2005 History of Changes

Sponsor:	National Taiwan University Hospital
Information provided by:	National Taiwan University Hospital
ClinicalTrials.gov Identifier:	NCT00155376

Purpose

Morphine can induce constriction of sphincter of oddi and glucagon can facilitate bile secretion and dilatation of bile duct. We conduct this randomized double blinded study to evaluate the effect of enhancement in MRCP using intravenous morphine and glucagon.

Condition	Intervention	Phase
Liver Disease	Drug: morphine and glucagon	Phase IV

Study Type:	Interventional
Study Design:	Diagnostic, Randomized, Double-Blind, Uncontrolled, Parallel Assignment

Resource links provided by NLM:

MedlinePlus related topics: Liver Diseases

Drug Information available for: Glucagon Glucagon-like peptide 1

U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:

MRCP visibility

Estimated Enrollment:	100
Study Start Date:	September 2005
Estimated Study Completion Date:	September 2005

Detailed Description:

Eligibility

Ages Eligible for Study:	20 Years to 75 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

normal volunteer
living liver donor

Exclusion Criteria:

COPD
chronic liver disease
hypersensitive to glucagon
DM
insulinoma
glucagonoma
pregnancy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00155376

Contacts

Contact: Yuan-Heng Mo, MD

jamesmyh@ha.mc.ntu.edu.tw

Locations

Taiwan, province of Taiwan
National Taiwan University Hospital	Recruiting
Taipei, province of Taiwan, Taiwan, 100
Contact: Yuan-Heng Mo, MD jamesmyh@ha.mc.ntu.edu.tw

Sponsors and Collaborators

National Taiwan University Hospital

Investigators

Study Chair:

Hon-Man Liu, MD

National Taiwan University Hospital

More Information

No publications provided

Study ID Numbers:	940104
Study First Received:	September 8, 2005
Last Updated:	November 25, 2005
ClinicalTrials.gov Identifier:	NCT00155376 History of Changes
Health Authority:	Taiwan: Department of Health

Additional relevant MeSH terms:

Morphine
Liver Diseases
Glucagon
Physiological Effects of Drugs
Hormones, Hormone Substitutes, and Hormone Antagonists
Gastrointestinal Agents
Central Nervous System Depressants
Narcotics
Hormones

Pharmacologic Actions
Digestive System Diseases
Sensory System Agents
Therapeutic Uses
Peripheral Nervous System Agents
Analgesics
Central Nervous System Agents
Analgesics, Opioid

ClinicalTrials.gov processed this record on February 08, 2010