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| Sponsor: | Alberta Cancer Board |
|---|---|
| Information provided by: | Alberta Cancer Board |
| ClinicalTrials.gov Identifier: | NCT00124488 |
Purpose
Standard treatment for non-operable cervix cancer is radiation and chemotherapy. This treatment combination can result in significant radiation side-effects involving the bladder, small bowel and rectum. To improve results with radiation/chemotherapy, higher radiation doses have been tried for cervix cancer patients. Results from using higher radiation doses show that cervix tumours may be better controlled, but the radiation side-effects are worsened. Intensity modulated radiotherapy (IMRT) and Tomotherapy are new radiation planning and delivery technologies which may allow for delivery of higher radiation doses with less damage to normal organs. The purpose of this project is to determine whether or not IMRT and/or Tomotherapy technology can produce radiation plans that deliver higher doses of radiation to the tumor and lower doses to normal organs when compared to standard radiation plans. The results from this project will provide the basis for possibly treating future cervix cancer patients with Tomotherapy and providing them with improved cure rates along with decreased rates of radiation side effects. No patients will be treated on this protocol, as the investigators plan to only compare radiation dose calculations from different treatment plans created for test cervix cancer cases. There will be absolutely no patient contact in this protocol.
| Condition | Intervention |
|---|---|
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Cervix Neoplasm |
Device: Tomotherapy Treatment Planning |
| Study Type: | Observational |
| Study Design: | Retrospective |
| Official Title: | Comparison of Tomotherapy Versus Intensity-Modulated Step-and-Shoot and Conventional Radiation Treatment Plans for Patients With Locally-Advanced Squamous Cell Carcinoma of the Cervix |
| Estimated Enrollment: | 10 |
| Study Start Date: | June 2005 |
| Estimated Study Completion Date: | November 2005 |
Show Detailed Description
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations
More Information
| Study ID Numbers: | NA-15-0004 |
| Study First Received: | July 26, 2005 |
| Last Updated: | September 22, 2008 |
| ClinicalTrials.gov Identifier: | NCT00124488 History of Changes |
| Health Authority: | Canada: Health Canada |
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radiotherapy planning computer assisted radiotherapy conformal |
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Neoplasms by Histologic Type Genital Neoplasms, Female Uterine Diseases Urogenital Neoplasms Carcinoma Genital Diseases, Female Uterine Cervical Neoplasms |
Neoplasms Uterine Cervical Diseases Neoplasms by Site Uterine Neoplasms Neoplasms, Squamous Cell Carcinoma, Squamous Cell Neoplasms, Glandular and Epithelial |