Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography
The purpose of this study is to examine the blood flow in acetabulum after periacetabular osteotomy by Positron Emission Tomography (PET).
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography|
- changes in blood flow [ Time Frame: within the first three weeks after operation ] [ Designated as safety issue: No ]
- fluoride uptake [ Time Frame: within the first three weeks after operation ] [ Designated as safety issue: No ]
|Study Start Date:||January 2004|
|Study Completion Date:||August 2009|
|Primary Completion Date:||January 2008 (Final data collection date for primary outcome measure)|
Procedure: Periacetabular osteotomy
osteotomy of the pelvis to increase acetabular coverage
Other Name: PAO
As a consequence of periacetabular osteotomy the blood flow in acetabulum is decreased. After periacetabular osteotomy has been performed there is fine contact between the osteotomised acetabulum and the rest of the pelvis and the potential for healing is good. However, it has not been investigated how much the blood flow in acetabulum is changed after surgery. The blood flow is considered to be vital for how the pelvis heals after surgery. Most likely, the blood flow is important in relation to which degree osteoarthritis can be prevented after periacetabular osteotomy.
It is possible to estimate the blood flow by Positron Emission Tomography of the dysplastic hip joint pre- and postoperatively. In this study the blood flow and fluoride uptake is quantified by Positron emission tomography based on measurements of O-15 water and F-18 fluoride.
|Orthopaedic Center, Aarhus University Hospital|
|Aarhus, Denmark, 8000|
|Principal Investigator:||Kjeld Søballe, MD, Prof.||Orthopaedic Center, Aarhus University Hospital, Aarhus, Denmark|