The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women - Full Text View

The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

This study is currently recruiting participants.
Verified by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), June 2008

Sponsored by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov Identifier:	NCT00072917

Purpose

This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.

Condition

Obesity
Thinness
Weight Gain

MedlinePlus related topics:

Obesity

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective

Official Title:	The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

Further study details as provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

Biospecimen Retention: Samples With DNA

Biospecimen Description:

Blood and urine

Estimated Enrollment:	100
Study Start Date:	October 2003
Estimated Study Completion Date:	June 2008

Eligibility

Ages Eligible for Study:	25 Years to 35 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Subjects have been recruited through advertisements in local news media and on the internet

Criteria

Half of the subjects will be women, half will be men,
age 25-35,
a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI>30.
Subjects should not engage in planned physical activity more than 3 hrs per week.
For the obesity prone group there should be at least 1 1st degree relative with a BMI>30.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00072917

Locations


United States, Colorado
	University of Colorado Health Sciences Center	Recruiting
	Denver, Colorado, United States, 80262
	Contact: Sandra VonKaenel, BS 303-315-9005 sandra.vonkaenel@uchsc.edu
	Contact: Daniel H Bessesen, MD (303) 436-5910 daniel.bessesen@uchsc.edu
	Principal Investigator: Daniel H Bessesen, MD

Sponsors and Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

More Information

Responsible Party:	University of Colorado School of Medicine ( Daniel H. Bessesen, MD )
Study ID Numbers:	OVOPOB DK62874, DK62874
First Received:	November 12, 2003
Last Updated:	June 6, 2008
ClinicalTrials.gov Identifier:	NCT00072917
Health Authority:	United States: Federal Government

Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

obesity

thinness

weight gain

physical activity

diet

fat oxidation

hunger

feeding behavior

overfeeding

Study placed in the following topic categories:

Body Weight

Signs and Symptoms

Obesity

Thinness

Body Weight Changes

Nutrition Disorders

Overweight

Overnutrition

Weight Gain

ClinicalTrials.gov processed this record on October 10, 2008