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Evaulation of Interaction Between Herbal Products and Anticoagulants

This study is enrolling participants by invitation only.

Sponsored by: National Center for Complementary and Alternative Medicine (NCCAM)
Information provided by: National Center for Complementary and Alternative Medicine (NCCAM)
ClinicalTrials.gov Identifier: NCT00071682
  Purpose

The purpose of this study is to determine if the use of herbal products interferes with normal anticoagulation, leading to either excessive thinning of the blood and bleeding problems or inadequate thinning of the blood and clotting problems. Many patients who are on long term anticoagulation, or blood thinning, for a variety of medical problems, also take herbal products. It is not yet known whether use of herbal products interferes with this anticoagulation, and puts patients at risk for bleeding or clotting. This study will carefully monitor patients who are taking herbs and anticoagulants to determine if their laboratory tests show signs of being affected by the herbs. The study will ask all patients about their herbal product use, so all reported herbs will be included and monitored.


Condition
Coagulation Disorders

Genetics Home Reference related topics:   hemophilia   

MedlinePlus related topics:   Bleeding Disorders   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Natural History, Longitudinal, Defined Population, Prospective Study
Official Title:   Early Identification of Adverse Reactions to Herbs

Further study details as provided by National Center for Complementary and Alternative Medicine (NCCAM):

Estimated Enrollment:   2000
Study Start Date:   October 2007
Estimated Study Completion Date:   March 2008

  Eligibility
Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion criteria:

  • Taking longer-term (>6 months) anticoagulation
  • Enrolled in one of Kaiser Permanente Northern California anticoagulation clinics
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00071682

Locations
United States, California
San Francisco VA Medical Center    
      San Francisco, California, United States, 94121

Sponsors and Collaborators

Investigators
Principal Investigator:     Stephen Bent, MD     University of California, San Francisco    
  More Information


Study ID Numbers:   K08 AT001338-01
First Received:   October 29, 2003
Last Updated:   October 1, 2007
ClinicalTrials.gov Identifier:   NCT00071682
Health Authority:   United States: Federal Government

Keywords provided by National Center for Complementary and Alternative Medicine (NCCAM):
herbal medicine  
alternative medicines  
anticoagulation  
side effects
bleeding
clotting

Study placed in the following topic categories:
Hemorrhagic Disorders
Hematologic Diseases
Blood Coagulation Disorders
Vascular Diseases
Hemorrhage
Hemostatic Disorders

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on October 07, 2008




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