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High Intensity Light Therapy in Alzheimer's Disease

This study has been completed.

Sponsored by: National Center for Complementary and Alternative Medicine (NCCAM)
Information provided by: National Center for Complementary and Alternative Medicine (NCCAM)
ClinicalTrials.gov Identifier: NCT00065689
  Purpose

The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the best timing for the light therapy. The light levels being used in the study have been shown to improve depression in persons with seasonal affective disorder (SAD) and to relieve sleep problems in persons with jet lag and other body rhythm disturbances. Because persons with AD often will not remain still in front of a fluorescent panel, this project has involved renovations in the study units that provide for even, regulated, high-intensity light in all public areas of the study settings.


Condition Intervention Phase
Alzheimer's Disease
Dementia
Device: high-intensity light therapy
Phase III

Genetics Home Reference related topics:   Alzheimer disease   Dementia  

MedlinePlus related topics:   Alzheimer's Caregivers   Alzheimer's Disease   Dementia  

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Randomized, Single Blind, Dose Comparison, Crossover Assignment, Efficacy Study
Official Title:   High Intensity Light Therapy in Alzheimer's Disease

Further study details as provided by National Center for Complementary and Alternative Medicine (NCCAM):

Estimated Enrollment:   107
Study Start Date:   March 2003
Estimated Study Completion Date:   September 2005

Detailed Description:

See Brief Summary

  Eligibility
Ages Eligible for Study:   55 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Inclusion criteria:

  • Diagnosis of dementia
  • Residence on study units

Exclusion criteria:

  • Bipolar disorder
  • Severe retinal (eye) disease
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00065689

Locations
United States, North Carolina
John Umstead Hospital    
      Butner, North Carolina, United States, 27514

Sponsors and Collaborators

Investigators
Principal Investigator:     Philip D. Sloane, MD, MPH    
  More Information

Study ID Numbers:   R01 AT000212-01A1, SloaneP
First Received:   July 31, 2003
Last Updated:   July 24, 2006
ClinicalTrials.gov Identifier:   NCT00065689
Health Authority:   United States: Federal Government

Keywords provided by National Center for Complementary and Alternative Medicine (NCCAM):
Alzheimer's disease  
light therapy  
long-term care  
depression
sleep
agitation

Study placed in the following topic categories:
Delirium, Dementia, Amnestic, Cognitive Disorders
Depression
Alzheimer Disease
Central Nervous System Diseases
Psychomotor Agitation
Neurodegenerative Diseases
Brain Diseases
Depressive Disorder
Dementia
Cognition Disorders
Delirium

Additional relevant MeSH terms:
Mental Disorders
Nervous System Diseases
Tauopathies

ClinicalTrials.gov processed this record on May 08, 2008