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| Sponsor: | National Center for Complementary and Alternative Medicine (NCCAM) |
|---|---|
| Information provided by: | National Center for Complementary and Alternative Medicine (NCCAM) |
| ClinicalTrials.gov Identifier: | NCT00065624 |
Purpose
The goal of this study is to determine whether a short treatment with lipoic acid, an antioxidant used in the treatment of diabetic neuropathy, improves blood vessel reactivity and decreases oxidant stress in persons with elevated blood cholesterol.
| Condition | Intervention | Phase |
|---|---|---|
|
Hypercholesterolemia |
Drug: lipoic acid |
Phase II |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
| Official Title: | Antioxidant Functions of Lipoic Acid |
Eligibility| Ages Eligible for Study: | 50 Years to 75 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion criteria:
Exclusion criteria:
Contacts and Locations
More Information
| Study ID Numbers: | R21 AT001062-01A2 |
| Study First Received: | July 29, 2003 |
| Last Updated: | September 28, 2007 |
| ClinicalTrials.gov Identifier: | NCT00065624 History of Changes |
| Health Authority: | United States: Federal Government |
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Lipoic acid F2-isoprostanes endothelial dysfunction natural product |
|
Hyperlipidemias Metabolic Diseases Antioxidants Vitamin B Complex Molecular Mechanisms of Pharmacological Action Growth Substances Physiological Effects of Drugs Protective Agents |
Pharmacologic Actions Vitamins Micronutrients Hypercholesterolemia Dyslipidemias Thioctic Acid Lipid Metabolism Disorders |