Effectiveness of Binge Eating Disorder Treatments - Full Text View

Purpose

This study will evaluate the long-term effectiveness of interpersonal psychotherapy, behavioral weight loss interventions, and guided self help treatments in treating binge eating disorder (BED).

Condition	Intervention	Phase
Eating Disorders	Behavioral: Interpersonal Therapy Behavioral: Behavioral Weight Loss Treatment Behavioral: Guided Self Help	Phase IV

MedlinePlus related topics:

Eating Disorders Weight Control

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study

Official Title:	Effectiveness of Psychological Treatments for BED

Further study details as provided by National Institute of Mental Health (NIMH):

Estimated Enrollment:	210
Study Start Date:	April 2002
Estimated Study Completion Date:	March 2005

Detailed Description:

BED is a serious condition that is associated with psychiatric comorbidity, psychosocial impairment, and obesity. Interpersonal psychotherapy (IPT), behavioral weight loss (BWL) interventions, and guided self help (GSH) treatments for BED have been evaluated, but the safest and most effective treatment has not yet been identified. This study will determine which of these three treatments is most effective in treating BED.

Participants are stratified by negative affect subtype and are randomly assigned for 6 months to one of three treatment groups: IPT, BWL, or GSH. IPT focuses on current interpersonal problems which are hypothesized to increase negative affect and lead to binge eating. BWL interventions involve the adoption of weight loss inducing behaviors. GSH is a shortened version of cognitive behavioral therapy that focuses directly on eating behavior. IPT and BWL patients have 20 treatment sessions; those receiving GSH have 10 sessions. Assessments are made pre-treatment, post-treatment, and at 6, 12, 18, and 24 months after treatment is complete.

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

DSM-IV criteria for Binge Eating Disorder
Body Mass Index (BMI) between 27 and 45

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00060762

Locations


United States, California
	W. Stewart Agras
	Stanford, California, United States, 94305

United States, Missouri
	Washington University School of Medicine
	St. Louis, Missouri, United States, 63100

United States, New Jersey
	Rutgers University Eating Disorder Clinic
	Piscataway, New Jersey, United States, 08854

Sponsors and Collaborators

National Institute of Mental Health (NIMH)

More Information

Responsible Party:	Stanford University ( W. Stewart Agras )
Study ID Numbers:	R01 MH63863, DSIR 83-ATAS
First Received:	May 12, 2003
Last Updated:	November 7, 2008
ClinicalTrials.gov Identifier:	NCT00060762
Health Authority:	United States: Federal Government

Keywords provided by National Institute of Mental Health (NIMH):

Weight Loss

Study placed in the following topic categories:

Body Weight

Bulimia Nervosa

Mental Disorders

Bulimia

Weight Loss

Eating Disorders

Additional relevant MeSH terms:

Pathologic Processes

Disease

ClinicalTrials.gov processed this record on November 30, 2008

Sponsored by:	National Institute of Mental Health (NIMH)
Information provided by:	National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:	NCT00060762