Treatment for Depression in the Primary Care Setting

This study has been completed.

First Received: February 25, 2003 Last Updated: August 19, 2008 History of Changes

Sponsor:	National Institute of Mental Health (NIMH)
Information provided by:	National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:	NCT00055328

Purpose

This study will compare a brief form of counseling to usual care for the treatment of minor depression in the primary care setting.

Condition	Intervention	Phase
Depression	Behavioral: Problem-Solving Treatment for Primary Care	Phase IV

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title:	Problem-Solving Treatment for Primary Care Depression

Resource links provided by NLM:

MedlinePlus related topics: Depression

U.S. FDA Resources

Further study details as provided by National Institute of Mental Health (NIMH):

Estimated Enrollment:	300
Study Start Date:	December 2002
Study Completion Date:	December 2006

Detailed Description:

Minor depression is one of the most common types of depressive disorders seen in primary care. The effectiveness and tolerability of antidepressants in patients with minor depression is unclear, and the development of alternative treatments is necessary.

In the first phase of this study, participants are observed for 4 weeks to identify those most in need of depression-specific treatment. Participants are then exposed to the Problem-Solving Treatment for Primary Care (PST-PC), a six-session behavioral treatment for depression. After 4 weeks, patients who do not respond adequately to the treatment are randomly assigned to either continued PST-PC or to usual care for 9 weeks. Participants are followed for 6 months after the study.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Primary care patient at Dartmouth-Hitchcock Medical Center (DHMC)
Hamilton Depression Score >= 10 and minor depression at time of entry and after 4 weeks of observation

Exclusion Criteria:

Psychosis, Obsessive Compulsive Disorder (OCD), or Post Traumatic Stress Disorder (PTSD)
Active substance abuse
Receiving treatment for depression

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00055328

Locations

United States, New Hampshire
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756

Sponsors and Collaborators

National Institute of Mental Health (NIMH)

More Information

No publications provided

Study ID Numbers:	R01 MH62322, DATR A4-GPS
Study First Received:	February 25, 2003
Last Updated:	August 19, 2008
ClinicalTrials.gov Identifier:	NCT00055328 History of Changes
Health Authority:	United States: Federal Government

Additional relevant MeSH terms:

Depression
Mental Disorders
Mood Disorders
Depressive Disorder
Behavioral Symptoms

ClinicalTrials.gov processed this record on November 27, 2009