DISEASE CHARACTERISTICS:

• Histologically confirmed adenocarcinoma of the prostate* NOTE: *All other variants are excluded
• No evidence of metastatic prostate cancer by bone scan and chest x-ray

• Prior prostatectomy within the past 4-8 weeks required

  • Prostate-specific antigen value obtained within 6 months prior to prostatectomy

• High risk of disease progression

  • Weighted risk of recurrence greater than 2.84

PATIENT CHARACTERISTICS:

Age

• 18 and over

Performance status

• ECOG 0-1

Life expectancy

• Not specified

Hematopoietic

• Neutrophil count at least 1,500/mm^3
• Platelet count at least 100,000/mm^3
• Hemoglobin at least 10 g/dL

Hepatic

• Bilirubin no greater than upper limit of normal (ULN)
• AST/ALT no greater than 1.5 times ULN if alkaline phosphatase no greater than ULN OR
• Alkaline phosphatase no greater than 4 times ULN if AST and ALT no greater than ULN
• No acute hepatitis

Renal

• Creatinine less than 1.5 times ULN
• No uncontrolled hypercalcemia

Cardiovascular

• No uncontrolled cardiac arrhythmias
• No uncontrolled angina
• No uncompensated congestive heart failure
• No superior vena cava syndrome

Other

• Fertile patients must use effective contraception during and for 1 year after study
• No other prior malignancy except adequately treated nonmelanoma skin cancer or a curatively treated malignancy (including superficial bladder cancer) without evidence of disease for the past 5 years
• No peripheral neuropathy greater than grade 1
• No other unstable medical condition
• No active infection
• No gastrointestinal bleeding
• No uncontrolled diabetes
• No dementia
• No seizures
• No psychological, familial, sociological, or geographical condition or other circumstance that would preclude study completion or follow-up
• No history of hypersensitivity to products containing polysorbate 80

PRIOR CONCURRENT THERAPY:

Biologic therapy

• No concurrent anticancer biologic therapy

Chemotherapy

• No prior systemic chemotherapy for prostate cancer
• No other concurrent systemic anticancer chemotherapy

Endocrine therapy

• No prior systemic hormonal therapy for prostate cancer
• No concurrent corticosteroids (except inhaled or topical corticosteroids)
• No concurrent systemic anticancer hormonal therapy
• No concurrent dehydroepiandrosterone (DHEA)

Radiotherapy

• No prior radiotherapy
• No radiotherapy during and for at least 30 days after study

Surgery

• See Disease Characteristics

Other

• No other prior systemic anticancer therapy
• No prior enrollment into this study

• No other concurrent alternative therapies including the following:

  • Saw palmetto
  • Lycopene
  • PC-SPES (all types)
• No other concurrent anticancer therapy
• No other concurrent systemic therapy