Marijuana for HIV-Related Peripheral Neuropathy
To evaluate whether smoked marijuana reduces pain in people with HIV-related peripheral neuropathy.
Peripheral Nervous System Diseases
Drug: Smoked Marijuana
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||Effects of Marijuana on Neuropathic Pain in HIV-Related Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Study.|
- Change in level of HIV-related neuropathic pain as recorded on a 100mm Visual Analog Scale.
- Change in level of experimentally-induced pain.
|Study Start Date:||January 2003|
|Estimated Study Completion Date:||April 2005|
The study will include subjects with peripheral neuropathy caused either by HIV-disease or antiretroviral medication for the treatment of HIV. A neurologist will conduct a neurological and pain evaluation to determine eligibility for the study. Subjects who meet all eligibility criteria will be admitted to the General Clinical Research Center at San Francisco General Hospital for seven days. Subjects will be randomized (like a toss of a coin) to smoke marijuana or a placebo (cigarettes with no THC).
|United States, California|
|University of California, San Francisco Community Consortium|
|San Francisco, California, United States, 94110|
|Principal Investigator:||Donald I Abrams, M.D.||UCSF Community Consortium|