Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

This study has been completed.
Sponsor:
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00043992
First received: August 16, 2002
Last updated: September 1, 2006
Last verified: September 2006
  Purpose

To examine the role of outdoor pollen grains and fungal spores in the exacerbation of asthma and to produce forecasting models to predict days of high concentration.


Condition
Asthma

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal

Resource links provided by NLM:


Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Estimated Enrollment: 1000
Study Start Date: July 2001
Detailed Description:

Asthma is a growing problem, and outdoor allergens play a role in exacerbation of many cases. A clearer understanding of this role and its magnitude, and a means of controlling the effects of outdoor allergen exposures is needed. We propose Poisson time-series and conditional panel studies to test these hypotheses: 1) The incidence of acute asthma attacks, as measured by urgent care inhalation treatments and hospitalizations for asthma, has a dose-dependent relationship with exposure to specific outdoor allergens; 2) Specific sensitization to outdoor allergens is a risk factor for having an acute attack; and 3) Exposure conditions that lead to acute asthma attacks can be forecast, creating an opportunity to reduce asthma morbidity and mortality ny targeting pretreatment and/or exposure controls.

  Eligibility

Ages Eligible for Study:   15 Years to 50 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Must be a member of the Fallon HMO and be treated for acute asthma exacerbation.

  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00043992

Locations
United States, Massachusetts
Fallon Clinic and Fallon Community Health Plan
Worcester, Massachusetts, United States, 01605
Sponsors and Collaborators
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00043992     History of Changes
Other Study ID Numbers: 9744-CP-001
Study First Received: August 16, 2002
Last Updated: September 1, 2006
Health Authority: United States: Federal Government

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
Asthma
Allergens

Additional relevant MeSH terms:
Asthma
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases

ClinicalTrials.gov processed this record on August 01, 2014