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| Sponsor: | National Institute of Environmental Health Sciences (NIEHS) |
|---|---|
| Information provided by: | National Institute of Environmental Health Sciences (NIEHS) |
| ClinicalTrials.gov Identifier: | NCT00043992 |
Purpose
To examine the role of outdoor pollen grains and fungal spores in the exacerbation of asthma and to produce forecasting models to predict days of high concentration.
| Condition |
|---|
|
Asthma |
| Study Type: | Observational |
| Study Design: | Natural History, Longitudinal, Defined Population, Prospective Study |
| Estimated Enrollment: | 1000 |
| Study Start Date: | July 2001 |
Asthma is a growing problem, and outdoor allergens play a role in exacerbation of many cases. A clearer understanding of this role and its magnitude, and a means of controlling the effects of outdoor allergen exposures is needed. We propose Poisson time-series and conditional panel studies to test these hypotheses: 1) The incidence of acute asthma attacks, as measured by urgent care inhalation treatments and hospitalizations for asthma, has a dose-dependent relationship with exposure to specific outdoor allergens; 2) Specific sensitization to outdoor allergens is a risk factor for having an acute attack; and 3) Exposure conditions that lead to acute asthma attacks can be forecast, creating an opportunity to reduce asthma morbidity and mortality ny targeting pretreatment and/or exposure controls.
Eligibility| Ages Eligible for Study: | 15 Years to 50 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Must be a member of the Fallon HMO and be treated for acute asthma exacerbation.
Contacts and Locations
More Information
| Study ID Numbers: | 9744-CP-001 |
| Study First Received: | August 16, 2002 |
| Last Updated: | September 1, 2006 |
| ClinicalTrials.gov Identifier: | NCT00043992 History of Changes |
| Health Authority: | United States: Federal Government |
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Asthma Allergens |
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Hypersensitivity Lung Diseases, Obstructive Immune System Diseases Respiratory Tract Diseases Bronchial Diseases |
Lung Diseases Hypersensitivity, Immediate Asthma Respiratory Hypersensitivity |