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Screening Patients With Central Nervous System Tumors for Participation in National Cancer Institute Clinical Trials
This study is currently recruiting participants.
Verified by National Cancer Institute (NCI), April 2008
First Received: July 8, 2002   Last Updated: May 7, 2009   History of Changes
Sponsor: National Cancer Institute (NCI)
Information provided by: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT00040924
  Purpose

RATIONALE: Screening tests may help doctors determine which patients are eligible for treatment on clinical trials.

PURPOSE: This clinical trial is screening patients with central nervous system tumors for participation in National Cancer Institute (NCI) clinical trials.


Condition Intervention
Brain and Central Nervous System Tumors
Lymphoma
Other: cytology specimen collection procedure
Other: physiologic testing

Study Type: Interventional
Study Design: Screening
Official Title: Eligibility Screening Of Patients With Central Nervous System Tumors For The National Cancer Institute's (NCI) Clinical Research Protocols

Resource links provided by NLM:


Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • Entry onto investigational study [ Designated as safety issue: No ]

Estimated Enrollment: 3000
Study Start Date: April 2002
Estimated Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Detailed Description:

OBJECTIVES:

  • Evaluate patients with central nervous system tumors for eligibility in NCI primary clinical research protocols.

OUTLINE: Patients undergo various diagnostic procedures and clinical testing to determine eligibility for participation in NCI CNS tumor primary clinical research protocols. Patients undergo imaging scans; laboratory testing of blood, cerebrospinal fluid, bone marrow, urine, and other specimens as needed to determine protocol eligibility; and other specific organ function tests.

PROJECTED ACCRUAL: A maximum of 3,000 patients will be accrued for this study within 5 years.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

DISEASE CHARACTERISTICS:

  • Diagnosis of CNS tumor or a history of a CNS tumor
  • Being evaluated for primary clinical research protocols within NCI

PATIENT CHARACTERISTICS:

Age:

  • Any age

Performance status:

  • Not specified

Life expectancy:

  • Not specified

Hematopoietic:

  • Not specified

Hepatic:

  • Not specified

Renal:

  • Not specified

Other:

  • No other concurrent serious medical condition that would preclude screening procedures

PRIOR CONCURRENT THERAPY:

Biologic therapy:

  • Not specified

Chemotherapy:

  • Not specified

Endocrine therapy:

  • Not specified

Radiotherapy:

  • Not specified

Surgery:

  • Not specified
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00040924

Locations
United States, Maryland
Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office Recruiting
Bethesda, Maryland, United States, 20892-1182
Contact: Clinical Trials Office - Warren Grant Magnusen Clinical Center     888-NCI-1937        
Sponsors and Collaborators
Investigators
Principal Investigator: Howard A. Fine, MD NCI - Neuro-Oncology Branch
  More Information

Additional Information:
No publications provided

Study ID Numbers: CDR0000069420, NCI-02-C-0186
Study First Received: July 8, 2002
Last Updated: May 7, 2009
ClinicalTrials.gov Identifier: NCT00040924     History of Changes
Health Authority: Unspecified

Keywords provided by National Cancer Institute (NCI):
childhood infratentorial ependymoma
childhood low-grade cerebral astrocytoma
childhood supratentorial ependymoma
childhood craniopharyngioma
childhood central nervous system germ cell tumor
recurrent adult brain tumor
ACTH-producing pituitary tumor
prolactin-producing pituitary tumor
growth hormone-producing pituitary tumor
recurrent pituitary tumor
TSH producing pituitary tumor
nonfunctioning pituitary tumor
adult brain stem glioma
adult craniopharyngioma
adult medulloblastoma
adult meningioma
adult glioblastoma
pituitary basophilic adenoma
prolactin secreting adenoma
pituitary eosinophilic adenoma
TSH secreting adenoma
pituitary chromophobe adenoma
childhood high-grade cerebral astrocytoma
childhood oligodendroglioma
adult anaplastic astrocytoma
childhood choroid plexus tumor
childhood grade I meningioma
childhood grade II meningioma
childhood grade III meningioma
adult oligodendroglioma

Additional relevant MeSH terms:
Lymphatic Diseases
Neoplasms
Neoplasms by Site
Immunoproliferative Disorders
Neoplasms by Histologic Type
Immune System Diseases
Nervous System Diseases
Central Nervous System Neoplasms
Lymphoproliferative Disorders
Lymphoma
Nervous System Neoplasms

ClinicalTrials.gov processed this record on November 27, 2009