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Insulin, Neurogenetics and Memory in Alzheimer's Disease

This study has been completed.

Sponsored by: Department of Veterans Affairs
Information provided by: Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT00018382
  Purpose

This study examines the use of insulin-sensitizing compounds, as therapeutic agents for cognitive impairment in Alzheimer's disease.


Condition Intervention Phase
Alzheimer Disease
Drug: rosiglitazone
Phase II

Genetics Home Reference related topics:   Alzheimer disease   

MedlinePlus related topics:   Alzheimer's Disease    Memory   

ChemIDplus related topics:   Insulin    Rosiglitazone    Rosiglitazone Maleate   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Randomized, Double-Blind, Placebo Control, Efficacy Study
Official Title:   Insulin, Neurogenetics and Memory in Alzheimer's Disease: A Novel Therapeutic Approach

Further study details as provided by Department of Veterans Affairs:

Study Start Date:   October 1999
Estimated Study Completion Date:   March 2003

  Eligibility
Ages Eligible for Study:   55 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Men and women with mild Alzheimer's Disease without serious medical or psychiatric comorbid conditions.

  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00018382

Locations
United States, Washington
VA Puget Sound Health Care System    
      Seattle, Washington, United States, 98108

Sponsors and Collaborators

Investigators
Investigator:     Steven Kahn, M.D.    
Investigator:     Sanjay Asthana, M.D.    
Investigator:     Alfred Fujimoto, M.D.    
  More Information

Study ID Numbers:   AGCG-012-98S
First Received:   July 3, 2001
Last Updated:   June 23, 2005
ClinicalTrials.gov Identifier:   NCT00018382
Health Authority:   United States: Federal Government

Study placed in the following topic categories:
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders
Alzheimer Disease
Central Nervous System Diseases
Neurodegenerative Diseases
Brain Diseases
Dementia
Rosiglitazone
Insulin
Cognition Disorders
Delirium

Additional relevant MeSH terms:
Hypoglycemic Agents
Physiological Effects of Drugs
Nervous System Diseases
Tauopathies
Pharmacologic Actions

ClinicalTrials.gov processed this record on September 05, 2008




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