Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

This study has been completed.

First Received: July 3, 2001 Last Updated: January 20, 2009 History of Changes

Sponsored by:	Department of Veterans Affairs
Information provided by:	Department of Veterans Affairs
ClinicalTrials.gov Identifier:	NCT00018356

Purpose

This study's primary objective is to determine the independent and combined effects of progressive resistance muscle strength training and testosterone on the development of sustainable improvements in physical function.

Condition	Intervention	Phase
Muscle Weakness Muscular Atrophy	Procedure: exercise Drug: testosterone	Phase IV

Study Type:	Interventional
Study Design:	Treatment
Official Title:	Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

Resource links provided by NLM:

Drug Information available for: Testosterone Propionate Methyltestosterone Testosterone Oxymesterone Testosterone enanthate Testosterone undecanoate

U.S. FDA Resources

Further study details as provided by Department of Veterans Affairs:

Study Start Date:	January 1999
Estimated Study Completion Date:	December 2003

Eligibility

Ages Eligible for Study:	65 Years and older
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No

Criteria

The study will be limited to those patients who are metabolically stable and free of metastatic cancer and limiting end organ disease. Their total serum testosterone must be less than 480 and PSA less than 10.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00018356

Locations

United States, Arkansas
Central Arkansas Veterans Healthcare System
North Little Rock, Arkansas, United States, 72114

Sponsors and Collaborators

Department of Veterans Affairs

More Information

No publications provided

Study ID Numbers:	AGCG-007-98S
Study First Received:	July 3, 2001
Last Updated:	January 20, 2009
ClinicalTrials.gov Identifier:	NCT00018356 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by Department of Veterans Affairs:

Aging
nutrition
rehabilitation

Study placed in the following topic categories:

Pathological Conditions, Anatomical
Antineoplastic Agents, Hormonal
Asthenia
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Methyltestosterone
Muscle Weakness
Hormones
Testosterone 17 beta-cypionate

Signs and Symptoms
Anabolic Agents
Testosterone
Muscular Diseases
Musculoskeletal Diseases
Neurologic Manifestations
Atrophy
Muscular Atrophy
Androgens

Additional relevant MeSH terms:

Pathological Conditions, Anatomical
Neuromuscular Manifestations
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Physiological Effects of Drugs
Nervous System Diseases
Hormones, Hormone Substitutes, and Hormone Antagonists
Methyltestosterone
Muscle Weakness
Hormones
Pharmacologic Actions
Testosterone 17 beta-cypionate

Signs and Symptoms
Anabolic Agents
Testosterone
Muscular Diseases
Pathologic Processes
Musculoskeletal Diseases
Therapeutic Uses
Neurologic Manifestations
Atrophy
Muscular Atrophy
Androgens

ClinicalTrials.gov processed this record on July 02, 2009