Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

This study has been completed.
Sponsor:
Information provided by:
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00018304
First received: July 3, 2001
Last updated: January 20, 2009
Last verified: December 2004
  Purpose

The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements in metabolic insulin action. In addition, the study will track whether these improvements are related to changes in blood pressure.


Condition Phase
Hypertension
Phase 1

Study Type: Observational
Official Title: Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

Resource links provided by NLM:


Further study details as provided by Department of Veterans Affairs:

  Eligibility

Ages Eligible for Study:   50 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Age 50 - 75 years, elevated blood pressure, BMI greater than 25 but less than 40 kg/m2

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00018304

Locations
United States, Minnesota
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Sponsors and Collaborators
Investigators
Investigator: Arthur Leon, M.D.
Investigator: Alan Blank, M.D.
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00018304     History of Changes
Other Study ID Numbers: AGCG-005-98S
Study First Received: July 3, 2001
Last Updated: January 20, 2009
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
blood pressure
insulin sensitivity
blood flow

Additional relevant MeSH terms:
Hypertension
Cardiovascular Diseases
Vascular Diseases
Insulin
Hypoglycemic Agents
Pharmacologic Actions
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on October 20, 2014