Multicenter Asthma Research Collaboration - Full Text View

Purpose

To study the epidemiology of emergency asthma by focusing on three Multicenter Asthma Research Collaboration (MARC) databases collected over a two-year period in adult and pediatric emergency departments.

Condition

Asthma
Lung Diseases

MedlinePlus related topics:

Asthma

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date:	July 1999
Estimated Study Completion Date:	June 2001

Detailed Description:

BACKGROUND:

The Multicenter Airway Research Collaboration (MARC) was created by 12 emergency physicians in May 1996 to determine the best management of acute asthma in the emergency department. The principal investigator of MARC, Dr. Carlos Camargo, formed the MARC Steering Committee to help guide this collaboration. The MARC Coordinating Center is based at the Massachusetts General Hospital (Boston, MA). Financial support for MARC has come from a variety of sources, including government, foundations, and industry. The NHLBI study used MARC databases.

DESIGN NARRATIVE:

Five representative aims were to: 1) characterize acute asthma management in urban emergency departments (EDs) and then compare current practice with that recommended in the 1997 national guidelines; 2) examine gender differences in acute asthma; 3) identify reasons why minority patients with asthma go to (and possibly prefer) the ED for their asthma care; 4) characterize important clinical subgroups, such as acute asthma among pregnant women and patients with sudden-onset severe acute asthma; and 5) examine risk factors for asthma hospitalization and for relapse after ED discharge.

Eligibility

Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No

Criteria

No eligibility criteria

Contacts and Locations

No Contacts or Locations Provided

More Information

Publications:

Emerman CL, Cydulka RK, Crain EF, Rowe BH, Radeos MS, Camargo CA Jr. Prospective multicenter study of relapse after treatment for acute asthma among children presenting to the emergency department. J Pediatr. 2001 Mar;138(3):318-24.

Emond SD, Reed CR, Graff LG IV, Clark S, Camargo CA Jr. Asthma education in the Emergency Department. On behalf of the MARC Investigators. Ann Emerg Med. 2000 Sep;36(3):204-11.

Study ID Numbers:	5110
First Received:	May 25, 2000
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00005563
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Hypersensitivity

Lung Diseases, Obstructive

Respiratory Tract Diseases

Lung Diseases

Hypersensitivity, Immediate

Asthma

Respiratory Hypersensitivity

Additional relevant MeSH terms:

Immune System Diseases

Bronchial Diseases

ClinicalTrials.gov processed this record on December 03, 2008

Sponsored by:	National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:	National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:	NCT00005563