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| Sponsored by: |
National Heart, Lung, and Blood Institute (NHLBI) |
| Information provided by: | National Heart, Lung, and Blood Institute (NHLBI) |
| ClinicalTrials.gov Identifier: | NCT00005467 |
Purpose
To develop a clinical severity index that could prospectively identify sickle cell disease patients who were at high risk for a turbulent clinical course and a poor prognosis.
| Condition |
|
Anemia, Sickle Cell Blood Disease |
| Genetics Home Reference related topics: | sickle cell disease |
| MedlinePlus related topics: | Anemia Sickle Cell Anemia |
| Study Type: | Observational |
| Study Design: | Natural History |
| Study Start Date: | January 1990 |
| Estimated Study Completion Date: | December 1992 |
DESIGN NARRATIVE:
Using the database, univariate analysis showed that factors associated with the occurrence of cerebrovascular accident (51 patients) included hematocrit, rate of change of pocked red cell count, and polymer fraction at 40 percent oxygen saturation (PF40). Only low hematocrit was predictive of death in the pediatric cohort. There were 45 disease-related deaths.
Eligibility
| Genders Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
No eligibility criteria
Contacts and Locations More Information
| Study ID Numbers: | 4912 |
| First Received: | May 25, 2000 |
| Last Updated: | June 23, 2005 |
| ClinicalTrials.gov Identifier: | NCT00005467 |
| Health Authority: | United States: Federal Government |
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