Study of Low Bone Mass in Premenopausal or Perimenopausal Women

This study has been completed.
Sponsor:
Collaborator:
Columbia University
Information provided by:
National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:
NCT00005101
First received: April 6, 2000
Last updated: June 23, 2005
Last verified: December 2003
  Purpose

OBJECTIVES:

I. Determine the possible causes of bone loss in premenopausal or perimenopausal women.


Condition
Osteoporosis

Study Type: Observational
Study Design: Primary Purpose: Screening

Resource links provided by NLM:


Further study details as provided by National Center for Research Resources (NCRR):

Study Start Date: February 1998
Detailed Description:

PROTOCOL OUTLINE: Patients undergo physical examination and complete history with emphasis on risk factors for osteoporosis and screening for occult secondary causes of osteoporosis through blood serum and 24 hour urine collection.

Patients with more than 6 months since prior bone mineral density measurements or who did not receive measurements at participating center, undergo dual energy x-ray absorptiometry over 30 minutes for bone mineral density measurements.

  Eligibility

Ages Eligible for Study:   16 Years to 54 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics--

  • Low bone mass (T score less than -2.0) with no secondary cause on routine exam
  • Premenopausal

OR

  • Perimenopausal

--Prior/Concurrent Therapy--

  • Chemotherapy: No prior or concurrent chemotherapeutic agents
  • Endocrine therapy: No prior or concurrent glucocorticoids or suppressive doses of thyroid hormone
  • Other: No prior or concurrent anticonvulsants

--Patient Characteristics--

  • Hematopoietic: No multiple myeloma
  • Other: No hyperparathyroidism No thyrotoxicosis No anorexia nervosa No Paget's disease of bone No rheumatoid arthritis No Cushing's syndrome No malabsorption syndrome No type I diabetes mellitus
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00005101

Locations
United States, New York
Columbia University College of Physicians and Surgeons
New York, New York, United States, 10032
Sponsors and Collaborators
Columbia University
Investigators
Study Chair: Elizabeth Shane Columbia University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00005101     History of Changes
Other Study ID Numbers: NCRR-M01RR00645-2738, CPMC-IRB-8414, CPMC-GCRC-2738
Study First Received: April 6, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):
disease-related problem/condition
osteoporosis
rare disease

Additional relevant MeSH terms:
Osteoporosis
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases

ClinicalTrials.gov processed this record on September 18, 2014