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Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups

This study has been completed.
Sponsor:
Collaborator:
Columbia University
Information provided by:
Office of Rare Diseases (ORD)
ClinicalTrials.gov Identifier:
NCT00004781
First received: February 24, 2000
Last updated: June 23, 2005
Last verified: February 1997
History of Changes
  Purpose

OBJECTIVES: I. Evaluate the development of oral manifestations of human immunodeficiency virus infection in relationship to the onset of immunologic alterations and systemic symptoms in different risk groups: gay/bisexual men, male intravenous drug users, and female intravenous drug users.

II. Evaluate the immune and inflammatory response to periodontal and other microbial pathogens.

III. Evaluate the bacterial species infecting the oral cavity in patients in these risk groups.


Condition
HIV Infections
Candidiasis, Oral

Study Type: Observational
Study Design: Primary Purpose: Screening

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Office of Rare Diseases (ORD):

Estimated Enrollment: 250
Study Start Date: September 1989
Detailed Description:

PROTOCOL OUTLINE:

Patients undergo a periodontal assessment every 6 months until medically unable to continue. The oral/dental exam includes saliva and gingival crevicular fluid analysis and, as indicated, oral photographs.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics-- Human immunodeficiency virus infection (HIV) seropositive or seronegative At risk for HIV, i.e.: Gay/bisexual men Male intravenous drug users Female intravenous drug users No acquired immunodeficiency syndrome Currently enrolled in Columbia Presbyterian Medical Center protocol "The Natural History and Progression of HIV Infection"

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004781

Sponsors and Collaborators
National Institute of Dental and Craniofacial Research (NIDCR)
Columbia University
Investigators
Study Chair: Ira B. Lamster Columbia University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00004781     History of Changes
Other Study ID Numbers: 199/11861, CU-SDOS-5059
Study First Received: February 24, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by Office of Rare Diseases (ORD):
HIV-associated candidiasis
candidiasis
disease-related problem/condition
fungal infection
 immunologic disorders and infectious disorders
infection
rare disease

Additional relevant MeSH terms:
Acquired Immunodeficiency Syndrome
HIV Infections
Candidiasis
Candidiasis, Oral
Oral Manifestations
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
 Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Slow Virus Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Mycoses
Mouth Diseases
Stomatognathic Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on May 21, 2013