Public Access Defibrillation (PAD) Community Trial

This study has been completed.

First Received: February 9, 2000 Last Updated: December 1, 2005 History of Changes

Sponsor:	National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:	National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:	NCT00004560

Purpose

To measure survival to hospital discharge of patients with out-of-hospital cardiac arrest in community units (e.g., apartment or office buildings, gated communities, sports venues, senior centers, shopping malls) served by trained non-medical responders using automated external defibrillators (AEDs), an approach called Public Access Defibrillation, compared to units receiving the traditional optimum community standard of care (i.e., rescuers trained to recognize a cardiac emergency, call 911, and initiate CPR).

Condition	Intervention	Phase
Arrhythmia Heart Arrest Heart Diseases Myocardial Infarction Ventricular Fibrillation Death, Sudden, Cardiac	Device: defibrillator	Phase III

Study Type:	Interventional
Study Design:	Treatment, Randomized

Resource links provided by NLM:

Genetics Home Reference related topics: Brugada syndrome short QT syndrome

MedlinePlus related topics: Arrhythmia Cardiac Arrest Heart Attack Heart Diseases

U.S. FDA Resources

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date:	September 1999
Estimated Study Completion Date:	February 2004

Show Detailed Description

Eligibility

Ages Eligible for Study:	18 Years to 75 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

No eligibility criteria

Contacts and Locations

No Contacts or Locations Provided

More Information

Publications:

[No authors listed] The Public Access Defibrillation (PAD) Trial. Study design and rationale. Resuscitation. 2003 Feb;56(2):135-147.

Mosesso VN Jr, Brown LH, Greene HL, Schmidt TA, Aufderheide TP, Sayre MR, Stephens SW, Travers A, Craven RA, Weisfeldt ML; The PAD Trial Investigators. Conducting research using the emergency exception from informed consent: the Public Access Defibrillation (PAD) Trial experience. Resuscitation. 2004 Apr;61(1):29-36.

Sayre MR, Travers AH, Daya M, Greene HL, Salive ME, Vijayaraghavan K, Craven RA, Groh WJ, Hallstrom AP; PAD Investigators. Measuring survival rates from sudden cardiac arrest: the elusive definition. Resuscitation. 2004 Jul;62(1):25-34.

[No authors listed] The Public Access Defibrillation (PAD) Trial. Study design and rationale. Resuscitation. 2003 Feb;56(2):135-147.

Hallstrom AP, Ornato JP, Weisfeldt M, Travers A, Christenson J, McBurnie MA, Zalenski R, Becker LB, Schron EB, Proschan M; Public Access Defibrillation Trial Investigators. Public-access defibrillation and survival after out-of-hospital cardiac arrest. N Engl J Med. 2004 Aug 12;351(7):637-46.

Nichol G, Wells GA, Kuntz K, Feeny D, Longstreth W, Mahoney B, Mann C, Lucas R, Henry M, Huszti E, Birnbaum A. Methodological design for economic evaluation in Public Access Defibrillation (PAD) trial. Am Heart J. 2005 Aug;150(2):202-8.

Powell J, Van Ottingham L, Schron E. Public defibrillation: increased survival from a structured response system. J Cardiovasc Nurs. 2004 Nov-Dec;19(6):384-9.

Richardson LD, Gunnels MD, Groh WJ, Peberdy MA, Pennington S, Wilets I, Campbell V, Van Ottingham L, McBurnie MA; PAD Trial Investigators. Implementation of community-based public access defibrillation in the PAD trial. Acad Emerg Med. 2005 Aug;12(8):688-97.

Birnbaum A, McBurnie MA, Powell J, Ottingham LV, Riegel B, Potts J, Hedges JR; for the PAD Investigators. Modeling instructor preferences for CPR and AED competence estimation. Resuscitation. 2005 Mar;64(3):333-9.

Riegel B, Birnbaum A, Aufderheide TP, Thode HC Jr, Henry MC, Van Ottingham L, Swor R; PAD Investigators. Predictors of cardiopulmonary resuscitation and automated external defibrillator skill retention. Am Heart J. 2005 Nov;150(5):927-32.

Study ID Numbers:	128
Study First Received:	February 9, 2000
Last Updated:	December 1, 2005
ClinicalTrials.gov Identifier:	NCT00004560 History of Changes
Health Authority:	United States: Federal Government

Additional relevant MeSH terms:

Death
Heart Diseases
Myocardial Ischemia
Vascular Diseases
Heart Arrest
Ischemia
Necrosis
Pathologic Processes

Death, Sudden
Cardiovascular Diseases
Death, Sudden, Cardiac
Infarction
Myocardial Infarction
Ventricular Fibrillation
Arrhythmias, Cardiac

ClinicalTrials.gov processed this record on November 27, 2009