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Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

This study has been completed.

Sponsors and Collaborators: National Institute of Mental Health (NIMH)
University of Virginia
Information provided by: National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier: NCT00004451
  Purpose

This study will determine whether glucose facilitates memory in healthy elderly people and those with Parkinson's disease.


Condition Intervention
Parkinson Disease
Drug: Glucose

Genetics Home Reference related topics:   familial paroxysmal nonkinesigenic dyskinesia    Parkinson disease   

MedlinePlus related topics:   Parkinson's Disease   

Drug Information available for:   Dextrose   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Randomized, Double-Blind

Further study details as provided by National Institute of Mental Health (NIMH):

Estimated Enrollment:   120
Study Start Date:   March 1998

Detailed Description:

Subjects fast for 8 hours before receiving a test to determine their blood glucose levels. Following this test, subjects are randomized to receive either a glucose or saccharin sweetened drink. A series of memory tests and an additional 3 blood glucose level tests are administered approximately 15 minutes later. A minimum of 1 week afterward, the subjects return and receive the alternate sweetener followed by additional memory tests.

  Eligibility
Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion Criteria:

  • Three groups of subjects are eligible for this study: Healthy young adults between ages 18 and 30; Healthy elderly adults between ages 60 and 90; AND Anyone diagnosed with Parkinson's disease

Exclusion Criteria:

  • Prior surgery to remove part of the stomach
  • Diabetes, Addison's, or Cushing's diseases
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00004451

Locations
United States, Virginia
University of Virginia    
      Charlottesville, Virginia, United States, 22908

Sponsors and Collaborators

Investigators
Study Chair:     Carol A. Manning     University of Virginia    
  More Information


Study ID Numbers:   199/13548, K07 MH01197
First Received:   October 18, 1999
Last Updated:   November 29, 2005
ClinicalTrials.gov Identifier:   NCT00004451
Health Authority:   United States: Federal Government

Keywords provided by National Institute of Mental Health (NIMH):
Parkinson disease  
neurologic and psychiatric disorders  
rare disease  

Study placed in the following topic categories:
Ganglion Cysts
Movement Disorders
Mental Disorders
Parkinson Disease
Basal Ganglia Diseases
Rare Diseases
Central Nervous System Diseases
Healthy
Parkinsonian Disorders
Neurodegenerative Diseases
Brain Diseases

Additional relevant MeSH terms:
Nervous System Diseases

ClinicalTrials.gov processed this record on November 30, 2008




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