Ultraviolet Light Therapy for Systemic Lupus Erythematosus

This study is currently recruiting participants.

Verified by National Center for Research Resources (NCRR), January 2004

First Received: October 18, 1999 Last Updated: June 23, 2005 History of Changes

Sponsor:	National Center for Research Resources (NCRR)
Collaborator:	Louisiana State University
Information provided by:	National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:	NCT00004375

Purpose

OBJECTIVES:

I. Evaluate the mechanisms of ultraviolet A-1 light therapy in patients with systemic lupus erythematosus and normal controls.

Condition	Intervention	Phase
Systemic Lupus Erythematosus	Procedure: ultraviolet A-1 light treatment	Phase II

Study Type:	Interventional
Study Design:	Treatment

Resource links provided by NLM:

MedlinePlus related topics: Lupus

U.S. FDA Resources

Further study details as provided by National Center for Research Resources (NCRR):

Estimated Enrollment:	20
Study Start Date:	September 1991

Detailed Description:

PROTOCOL OUTLINE:

Treatment with ultraviolet A-1 light is administered 5 days a week for 6 weeks, at the lowest dose or frequency required to maintain a response. The dose and frequency are progressively decreased over the next 9 weeks.

Eligibility

Ages Eligible for Study:	15 Years to 70 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics--

Patients ages 15 to 70 with symptomatic systemic lupus erythematosus meeting American Rheumatism Association criteria and normal controls

--Prior/Concurrent Therapy--

No requirement for tetracycline or other photosensitizing drugs

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00004375

Locations

United States, Louisiana
Alton Ochsner Medical Foundation Hospital	Recruiting
New Orleans, Louisiana, United States, 70121
Contact: Jawed Alam 504-842-3314
General Clinical Research Center and Charity Hospital (University of Louisiana)	Recruiting
New Orleans, Louisiana, United States, 70112-2822
Contact: Hugh McGrath, Jr. 504-568-4630 hmcgra@lsuhsc.edu

Sponsors and Collaborators

National Center for Research Resources (NCRR)

Louisiana State University

Investigators

Study Chair:

Hugh McGrath, Jr.

Louisiana State University

More Information

Publications:

McGrath H, Martinez-Osuna P, Lee FA. Ultraviolet-A1 (340-400 nm) irradiation therapy in systemic lupus erythematosus. Lupus. 1996 Aug;5(4):269-74.

Study ID Numbers:	NCRR-M01RR05096-0002, LSUMC-1765, LSUMC-910067
Study First Received:	October 18, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00004375 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):

arthritis & connective tissue diseases
immunologic disorders and infectious disorders
rare disease
systemic lupus erythematosus

Additional relevant MeSH terms:

Autoimmune Diseases
Immune System Diseases
Lupus Erythematosus, Systemic
Connective Tissue Diseases

ClinicalTrials.gov processed this record on November 09, 2009