Combination Chemotherapy in Treating Children or Adolescents With Newly Diagnosed Stage III or Stage IV Lymphoblastic Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for lymphoblastic lymphoma.
PURPOSE: This randomized phase III trial is studying different regimens of combination chemotherapy to compare how well they work in treating children or adolescents with newly diagnosed stage III or stage IV lymphoblastic lymphoma.
Drug: daunorubicin hydrochloride
Drug: doxorubicin hydrochloride
Drug: leucovorin calcium
Drug: vincristine sulfate
Radiation: radiation therapy
|Study Design:||Allocation: Randomized
Primary Purpose: Treatment
|Official Title:||Randomized Phase III Study for the Treatment of Newly Diagnosed Disseminated Lymphoblastic Lymphoma or Localized Lymphoblastic Lymphoma|
- Event-free survival as assessed by time to treatment failure, occurrence of second malignant neoplasm, or death from any cause [ Designated as safety issue: No ]
- Survival as assessed by time to death [ Designated as safety issue: No ]
|Study Start Date:||June 2000|
|Primary Completion Date:||August 2008 (Final data collection date for primary outcome measure)|