Docetaxel in Treating Patients With Advanced Cancer of the Cervix
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of docetaxel in treating patients with advanced cancer of the cervix.
|Study Design:||Primary Purpose: Treatment|
|Official Title:||Neoadjuvant Chemotherapy With Docetaxel in Advanced Cervical Carcinoma|
|Study Start Date:||December 1997|
|Study Completion Date:||April 2004|
OBJECTIVES: I. Assess the antitumor activity of docetaxel as neoadjuvant chemotherapy in patients with locally advanced squamous cell carcinoma of the cervix. II. Assess the tumor response, toxic effect, and survival rate of this regimen in these patients.
OUTLINE: Patients receive docetaxel IV over 1 hour on day 1. Treatment is repeated every 3 weeks for 3 courses. Patients are followed every 3 months posttreatment.
PROJECTED ACCRUAL: A total of 16-35 patients will be accrued for this study.
|Unidad Oncologica Del Comahue|
|Neuquen, Argentina, 8300|
|Study Chair:||Carlos Teodoro Vallejo, MD||Grupo Oncologico Cooperativo del Sur|