Inclusion Criteria
Concurrent Medication:
Allowed:
Patients must have:
- AIDS.
- Recovered from their most recent episode of Pneumocystis carinii pneumonia (PCP). Patients must be at least 2 weeks status post therapy for acute PCP.
- Adequate pulmonary function (vital capacity = or > 65 percent of predicted; forced expiratory volume, 1 s = or > 55 percent of total FEV; and corrected pulmonary diffusion capacity > 50 percent of predicted).
- Patients must be free of acute medical problems.
Exclusion Criteria
Co-existing Condition:
Patients with the following are excluded:
- AIDS-defining opportunistic infection prior to entry such as toxoplasmosis and cryptococcosis.
- Pulmonary Kaposi's sarcoma.
- Asthma poorly controlled by medication.
- Receiving active therapy for tuberculosis.
Concurrent Medication:
Excluded:
- Active therapy for tuberculosis.
Patients with the following are excluded:
- Requiring ongoing active therapy for an opportunistic infection at time of study entry.
- AIDS-defining opportunistic infection prior to study entry such as toxoplasmosis and cryptococcosis.
- Pulmonary Kaposi's sarcoma.
- Unwilling to sign informed consent.
- Asthma poorly controlled by medication.
- Unwilling to cooperate with study procedures.
- Receiving active therapy for tuberculosis.
Prior Medication:
Excluded within 30 days of study entry:
- Antiretrovirals (other than zidovudine (AZT)).
- Immunomodulating agents.
- Corticosteroids.
Prior Treatment:
Excluded within 7 days of study entry:
- Transfusion.
- Patient cannot be transfusion dependent (requiring blood transfusion more than once per month).
Active substance abuse.