Inclusion Criteria
Patients must have:
- HIV-1 seropositivity.
- Diagnosis of AIDS or AIDS related complex (ARC).
- Failure to tolerate or respond to zidovudine (AZT) or decided to decline AZT therapy.
- The ability to sign a written informed consent form prior to treatment.
- A willingness to abstain from all other experimental therapy for HIV infection during the entire study period.
- A life expectancy of at least 3 months.
Exclusion Criteria
Co-existing Condition:
Patients with the following conditions or symptoms are excluded:
- Serious active opportunistic infections.
- Malignancies other than Kaposi's sarcoma.
Concurrent Medication:
Excluded:
- Zidovudine (AZT).
- Corticosteroids.
- Nonsteroidal anti-inflammatory agents (NSAI).
- Other experimental therapy.
Patients with the following are excluded:
- Serious active opportunistic infections.
- Malignancies other than Kaposi's sarcoma.
Prior Medication:
Excluded within 3 weeks of study entry:
- Zidovudine (AZT).
- Chemotherapy.
- Immunomodulators.
- Other experimental therapy.