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Brain Tissue Collection for Neuropathological Studies

This study is currently recruiting participants.
Verified by National Institutes of Health Clinical Center (CC), March 2008

Sponsored by: National Institute of Mental Health (NIMH)
Information provided by: National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier: NCT00001260
  Purpose

The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead to better treatments and potential cures for nervous system and mental disorders.

This study will ask relatives of deceased individuals to donate the brains of their deceased relatives to allow further study of neurological and psychiatric disorders....


Condition
Bipolar Disorder
Depression
Anxiety Disorders
Schizophrenia
Tourette's Syndrome
Brain Diseases

Genetics Home Reference related topics:   familial encephalopathy with neuroserpin inclusion bodies    familial paroxysmal nonkinesigenic dyskinesia    Tourette syndrome   

MedlinePlus related topics:   Anxiety    Bipolar Disorder    Brain Diseases    Child Mental Health    Depression    Mental Health    Schizophrenia    Suicide    Tourette Syndrome   

U.S. FDA Resources

Study Type:   Observational
Official Title:   Brain Procurement for the Neuropathology Section, CBDB

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment:   2000
Study Start Date:   May 1990

Detailed Description:

The knowledge of how affected tissue deviates from normal control tissue is an integral part of fully understanding a neurological or psychiatric disorder. The purpose of this protocol is to establish a coordinating program with the pathology departments of the Washington, D.C. and metropolitan area hospitals and local medical examiner's offices for the donation of brain tissue.

  Eligibility
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Criteria
  • INCLUSION CRITERIA:

Brain tissue is needed from individuals suffering from a variety of neuropsychiatric disorders, especially schizophrenia, but also anxiety disorders, suicide, bipolar disorder, depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the like) and any form of dementia. In addition, brains from normal individuals without a history of neuropsychiatric disease will be needed for controls.

  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001260

Contacts
Contact: Joel E. Kleinman, M.D.     (301) 402-7909     kleinmaj@intra.nimh.nih.gov    

Locations
United States, District of Columbia
Office of the Chief Medical Examiner     Recruiting
      Washington, District of Columbia, United States, 20003
United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike     Recruiting
      Bethesda, Maryland, United States, 20892
United States, Virginia
Office of the Chief Medical Examiner     Recruiting
      Fairfax, Virginia, United States, 22032

Sponsors and Collaborators
  More Information


NIH Clinical Center Detailed Web Page  This link exits the ClinicalTrials.gov site
 

Publications:

Study ID Numbers:   900142, 90-M-0142
First Received:   November 3, 1999
Last Updated:   July 18, 2008
ClinicalTrials.gov Identifier:   NCT00001260
Health Authority:   United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):
Schizophrenia  
Neuropathology  
Neurochemistry  
Substance Abuse  
Bipolar Disorder  
Aging  
Normal Development  
Depression  
Anxiety Disorders  
Suicide
Dementia
Depression
Bipolar Disorder
Neuropsychiatric Disorders
Suicide
Tourette's Syndrome
Normal Controls
Schizophrenia

Study placed in the following topic categories:
Basal Ganglia Diseases
Suicide
Brain Diseases
Neurodegenerative Diseases
Tics
Schizophrenia
Affective Disorders, Psychotic
Heredodegenerative Disorders, Nervous System
Mental Disorders
Movement Disorders
Mental Disorders Diagnosed in Childhood
Psychotic Disorders
Dementia
Schizophrenia and Disorders with Psychotic Features
Depression
Ganglion Cysts
Bipolar Disorder
Central Nervous System Diseases
Tourette Syndrome
Tic Disorders
Depressive Disorder
Behavioral Symptoms
Anxiety Disorders
Genetic Diseases, Inborn
Mood Disorders
Gilles de la Tourette's syndrome

Additional relevant MeSH terms:
Pathologic Processes
Disease
Syndrome
Nervous System Diseases

ClinicalTrials.gov processed this record on October 06, 2008




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