Studies of the Immune Response in Normal Subjects and Patients With Disorders of the Immune System - Full Text View

Purpose

The goal of the protocol is to define the normal humoral and cellular immune responses to antigens in volunteers and to define abnormalities of these immune responses in patients with immunodeficiency diseases or cancer. In vitro assays and in vivo skin tests and immunization with antigens will be utilized.

Condition

Immunologic Deficiency Syndromes
Neoplasms

MedlinePlus related topics:

Cancer

U.S. FDA Resources

Study Type:	Observational

Official Title:	Studies of the Immune Response in Normal Subjects and Patients With Disorders of the Immune System

Further study details as provided by National Institutes of Health Clinical Center (CC):

Study Start Date:	April 1977
Estimated Study Completion Date:	March 2000

Detailed Description:

The goal of the protocol is to define the normal humoral and cellular immune responses to antigens in volunteers and to define abnormalities of these immune responses in patients with immunodeficiency diseases or cancer. In vitro assays and in vivo skin tests and immunization with antigens will be utilized.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Patients will be studied if a disorder of the immune system is suspected.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001158

Locations


United States, Maryland
	National Cancer Institute (NCI)
	Bethesda, Maryland, United States, 20892

Sponsors and Collaborators

National Cancer Institute (NCI)

More Information

Publications:

Nelson DL, Blaese RM, Strober W, Bruce R, Waldmann TA. Constrictive pericarditis, intestinal lymphangiectasia, and reversible immunologic deficiency. J Pediatr. 1975 Apr;86(4):548-54.

Study ID Numbers:	770066, 77-C-0066
First Received:	November 3, 1999
Last Updated:	March 4, 2008
ClinicalTrials.gov Identifier:	NCT00001158
Health Authority:	United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):

Cellular Immunity

Humoral Immunity

Immunodeficiency Disease

Study placed in the following topic categories:

Immunologic Deficiency Syndromes

Additional relevant MeSH terms:

Neoplasms

Pathologic Processes

Disease

Immune System Diseases

Syndrome

ClinicalTrials.gov processed this record on December 03, 2008

Sponsored by:	National Cancer Institute (NCI)
Information provided by:	National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:	NCT00001158