Do Fish Oils Prevent Restenosis Post-Coronary Angioplasty? - Full Text View

Do Fish Oils Prevent Restenosis Post-Coronary Angioplasty?

This study has been completed.

Sponsored by:	National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:	National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:	NCT00000473

Purpose

To determine whether a dietary supplement of n-3 polyunsaturated fatty acids (PUFAs) derived from fish oil would decrease the restenosis rate in patients undergoing percutaneous transluminal coronary angioplasty (PTCA).

Condition	Intervention	Phase
Cardiovascular Diseases Coronary Disease Heart Diseases Myocardial Ischemia	Behavioral: dietary supplements Drug: fatty acids, omega-3 Behavioral: diet, fat-restricted	Phase III

MedlinePlus related topics:

Angioplasty Dietary Supplements Heart Diseases

Drug Information available for:

Fish oil

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Prevention, Randomized, Double-Blind

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date:

July 1989

Show Detailed Description

Eligibility

Ages Eligible for Study:	18 Years to 75 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Men and women with coronary heart disease in the native coronary arteries. Patients were symptomatic or had 50 percent or greater stenosis as defined by coronary angiography.

Patients had not undergone prior angioplasty.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000473

Sponsors and Collaborators

National Heart, Lung, and Blood Institute (NHLBI)

Investigators


Investigator:	Alexander Leaf	Massachusetts General Hospital

More Information

Publications:

Leaf A, Jorgensen MB, Jacobs AK, Cote G, Schoenfeld DA, Scheer J, Weiner BH, Slack JD, Kellett MA, Raizner AE, et al. Do fish oils prevent restenosis after coronary angioplasty? Circulation. 1994 Nov;90(5):2248-57.

Study ID Numbers:	62
First Received:	October 27, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00000473
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Coronary Disease

Heart Diseases

Myocardial Ischemia

Vascular Diseases

Ischemia

Additional relevant MeSH terms:

Pathologic Processes

Cardiovascular Diseases

ClinicalTrials.gov processed this record on December 03, 2008