ClinicalTrials.gov
 Home    Search    Study Topics    Glossary  
 

  Full Text View  
  Tabular View  
  Contacts and Locations  
  No Study Results Posted  
  Related Studies  
Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1

This study has been completed.

Sponsors and Collaborators: National Institute on Drug Abuse (NIDA)
University of Pennsylvania
Information provided by: National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier: NCT00000352
  Purpose

The purpose of this study is to determine if addition of dextromethorphan to a stable dose of methadone in opioid dependent subjects will significantly affect physical and psychological aspects of opioid tolerance.


Condition Intervention Phase
Opioid-Related Disorders
Substance-Related Disorders
Drug: Dextromethorphan
Phase II

Drug Information available for:   Methadone    Methadone hydrochloride    Dextromethorphan    Dextromethorphan hydrobromide    Levomethorphan    Racemethorphan   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment
Official Title:   Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients

Further study details as provided by National Institute on Drug Abuse (NIDA):

Estimated Enrollment:   0
Study Start Date:   December 1996

  Eligibility
Ages Eligible for Study:   21 Years to 55 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Please contact site for information.

  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000352

Locations
United States, Pennsylvania
University of Pennsylvania    
      Philadelphia, Pennsylvania, United States, 19104 6178

Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
University of Pennsylvania

Investigators
Principal Investigator:     Charles O'Brien, M.D., Ph.D.     PDVAMC Treatment Research Center    
  More Information


Study ID Numbers:   NIDA-3-0012-1, Y01-3-0012-1
First Received:   September 20, 1999
Last Updated:   June 23, 2005
ClinicalTrials.gov Identifier:   NCT00000352
Health Authority:   United States: Federal Government

Study placed in the following topic categories:
Naphazoline
Oxymetazoline
Excitatory Amino Acids
Methadone
Guaifenesin
Phenylephrine
Mental Disorders
Dextromethorphan
Substance-Related Disorders
Disorders of Environmental Origin
Phenylpropanolamine
Opioid-Related Disorders

Additional relevant MeSH terms:
Respiratory System Agents
Neurotransmitter Agents
Pathologic Processes
Disease
Molecular Mechanisms of Pharmacological Action
Therapeutic Uses
Physiological Effects of Drugs
Excitatory Amino Acid Agents
Antitussive Agents
Central Nervous System Agents
Pharmacologic Actions
Excitatory Amino Acid Antagonists

ClinicalTrials.gov processed this record on December 03, 2008




Links to all studies - primarily for crawlers