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Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1
This study has been completed.
First Received: September 20, 1999   Last Updated: June 23, 2005   History of Changes
Sponsor: National Institute on Drug Abuse (NIDA)
Collaborator: University of Pennsylvania
Information provided by: National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier: NCT00000352
  Purpose

The purpose of this study is to determine if addition of dextromethorphan to a stable dose of methadone in opioid dependent subjects will significantly affect physical and psychological aspects of opioid tolerance.


Condition Intervention Phase
Opioid-Related Disorders
Substance-Related Disorders
Drug: Dextromethorphan
Phase II

Study Type: Interventional
Study Design: Treatment
Official Title: Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients

Resource links provided by NLM:


Further study details as provided by National Institute on Drug Abuse (NIDA):

Estimated Enrollment: 0
Study Start Date: December 1996
  Eligibility

Ages Eligible for Study:   21 Years to 55 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Please contact site for information.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000352

Locations
United States, Pennsylvania
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104 6178
Sponsors and Collaborators
University of Pennsylvania
Investigators
Principal Investigator: Charles O'Brien, M.D., Ph.D. PDVAMC Treatment Research Center
  More Information

No publications provided

Study ID Numbers: NIDA-3-0012-1, Y01-3-0012-1
Study First Received: September 20, 1999
Last Updated: June 23, 2005
ClinicalTrials.gov Identifier: NCT00000352     History of Changes
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Respiratory System Agents
Neurotransmitter Agents
Disease
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Disorders of Environmental Origin
Excitatory Amino Acid Agents
Opioid-Related Disorders
Pharmacologic Actions
Pathologic Processes
Mental Disorders
Therapeutic Uses
Substance-Related Disorders
Dextromethorphan
Antitussive Agents
Central Nervous System Agents
Excitatory Amino Acid Antagonists

ClinicalTrials.gov processed this record on February 08, 2010