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| Sponsors and Collaborators: |
National Institute on Drug Abuse (NIDA) University of Chicago |
|---|---|
| Information provided by: | National Institute on Drug Abuse (NIDA) |
| ClinicalTrials.gov Identifier: | NCT00000259 |
Purpose
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine sevoflurane versus isoflurane inhalation at subanesthetic concentrations on mood, pain, and psychomotor performance.
| Condition | Intervention | Phase |
|---|---|---|
|
Opioid-Related Disorders Substance-Related Disorders |
Drug: Nitrous oxide |
Phase II |
| Study Type: | Interventional |
| Study Design: | Treatment |
| Official Title: | Sevoflurane Vs Isoflurane Inhalation at Subanesthetic Concentrations |
Eligibility| Ages Eligible for Study: | 21 Years to 39 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Please contact site for information.
Contacts and Locations| United States, Illinois | |
| University of Chicago, Anesthesia & Critical Care | |
| Chicago, Illinois, United States, 60637 | |
| Principal Investigator: | James Zacny, Ph.D. | University of Chicago |
More Information
| Study ID Numbers: | NIDA-08391-11, R01-08391-11 |
| Study First Received: | September 20, 1999 |
| Last Updated: | June 23, 2005 |
| ClinicalTrials.gov Identifier: | NCT00000259 History of Changes |
| Health Authority: | United States: Federal Government |
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Nitrous Oxide Disorders of Environmental Origin Anesthetics Central Nervous System Depressants Opioid-Related Disorders Sevoflurane Anesthetics, Inhalation Mental Disorders |
Anesthetics, General Analgesics, Non-Narcotic Substance-Related Disorders Isoflurane Platelet Aggregation Inhibitors Peripheral Nervous System Agents Analgesics |
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Disease Nitrous Oxide Hematologic Agents Physiological Effects of Drugs Disorders of Environmental Origin Anesthetics Central Nervous System Depressants Opioid-Related Disorders Pharmacologic Actions Sevoflurane Anesthetics, Inhalation Pathologic Processes |
Sensory System Agents Analgesics, Non-Narcotic Mental Disorders Anesthetics, General Therapeutic Uses Substance-Related Disorders Isoflurane Platelet Aggregation Inhibitors Peripheral Nervous System Agents Analgesics Central Nervous System Agents |