Carbamazepine Treatment of Cocaine Dependence - 1

This study has been completed.

First Received: September 20, 1999 Last Updated: November 3, 2005 History of Changes

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) Medical University of South Carolina
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000242

Purpose

The purpose of this study is to compare the efficacy of carbamazepine in treatment of cocaine-dependence in patients with affective disorders.

Condition	Intervention	Phase
Cocaine-Related Disorders Substance-Related Disorders	Drug: Carbamazepine	Phase II

Study Type:	Interventional
Study Design:	Treatment
Official Title:	Carbamazepine Treatment of Cocaine Dependence

Resource links provided by NLM:

Drug Information available for: Cocaine hydrochloride Carbamazepine

U.S. FDA Resources

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Severity addiction
Amount of drug use
Affective stability
Medication compliance

Estimated Enrollment:	0
Study Start Date:	October 1992

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000242

Locations

United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425 742

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Medical University of South Carolina

Investigators

Principal Investigator:

Kathleen Brady, Ph.D.

Medical University of South Carolina

More Information

Publications:

(1) Brady KT et. al. Features of cocaine dependence with concurrent alcohol abuse. Drug and Alcohol Depend. 1995, 39(1):69-71. (2) Brady KT et. al. Personality disorder and assault history in substance-dependent individuals. Am J on Addictions. 1995, 4(4):306-312. (3) Dansky et. al. Use of self-report measures of crime-related posttraumatic stress disorder with substance use disordered patients. Journal of Substance Abuse Treatment. (in press). (4) Sonne an Presentation at CPDD meeting, 1996.

Study ID Numbers:	NIDA-07761-1, R29-07761-1
Study First Received:	September 20, 1999
Last Updated:	November 3, 2005
ClinicalTrials.gov Identifier:	NCT00000242 History of Changes
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Cocaine-Related Disorders
Tranquilizing Agents
Psychotropic Drugs
Disorders of Environmental Origin
Central Nervous System Depressants
Antimanic Agents
Carbamazepine

Mental Disorders
Analgesics, Non-Narcotic
Substance-Related Disorders
Analgesics
Peripheral Nervous System Agents
Cocaine
Anticonvulsants

Additional relevant MeSH terms:

Cocaine-Related Disorders
Tranquilizing Agents
Disease
Physiological Effects of Drugs
Psychotropic Drugs
Central Nervous System Depressants
Disorders of Environmental Origin
Antimanic Agents
Pharmacologic Actions
Pathologic Processes

Carbamazepine
Mental Disorders
Analgesics, Non-Narcotic
Sensory System Agents
Therapeutic Uses
Substance-Related Disorders
Analgesics
Peripheral Nervous System Agents
Central Nervous System Agents
Anticonvulsants

ClinicalTrials.gov processed this record on July 02, 2009