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IV Cocaine Abuse: A Laboratory Model - 4

This study has been completed.

Sponsors and Collaborators: National Institute on Drug Abuse (NIDA)
Columbia University
Information provided by: National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier: NCT00000215
  Purpose

The purpose of this study is to evaluate the effects of pergolide on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.


Condition Intervention Phase
Cocaine-Related Disorders
Drug: Pergolide
Phase II

Drug Information available for:   8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-    Cocaine hydrochloride    Pergolide    Pergolide mesylate   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment
Official Title:   IV Cocaine Abuse: A Laboratory Model

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Direct cocaine effects (cardio, subjective)
  • Interaction of cocaine/pergolide on cardio
  • Interaction of coc/pergolide on coc's subjective
  • Effects of pergolide on cocaine craving

Estimated Enrollment:   0
Estimated Study Completion Date:   December 2001

  Eligibility
Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Please contact site for information.

  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000215

Locations
United States, New York
Columbia University    
      New York, New York, United States, 10023

Sponsors and Collaborators

Investigators
Principal Investigator:     Richard Foltin, Ph.D.     Columbia University    
  More Information


Study ID Numbers:   NIDA-06234-4, R01-06234-4
First Received:   September 20, 1999
Last Updated:   June 23, 2005
ClinicalTrials.gov Identifier:   NCT00000215
Health Authority:   United States: Federal Government

Study placed in the following topic categories:
Cocaine-Related Disorders
Dopamine
Mental Disorders
Substance-Related Disorders
Disorders of Environmental Origin
Cocaine
Pergolide

Additional relevant MeSH terms:
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Dopamine Agents
Dopamine Agonists
Pharmacologic Actions

ClinicalTrials.gov processed this record on December 03, 2008




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