IV Cocaine Abuse: A Laboratory Model - 4

This study has been completed.

First Received: September 20, 1999 Last Updated: June 23, 2005 History of Changes

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) Columbia University
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000215

Purpose

The purpose of this study is to evaluate the effects of pergolide on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.

Condition	Intervention	Phase
Cocaine-Related Disorders	Drug: Pergolide	Phase II

Study Type:	Interventional
Study Design:	Treatment
Official Title:	IV Cocaine Abuse: A Laboratory Model

Resource links provided by NLM:

Drug Information available for: Cocaine hydrochloride Pergolide Pergolide mesylate

U.S. FDA Resources

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Direct cocaine effects (cardio, subjective)
Interaction of cocaine/pergolide on cardio
Interaction of coc/pergolide on coc's subjective
Effects of pergolide on cocaine craving

Estimated Enrollment:	0
Estimated Study Completion Date:	December 2001

Eligibility

Ages Eligible for Study:	18 Years to 45 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000215

Locations

United States, New York
Columbia University
New York, New York, United States, 10023

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Columbia University

Investigators

Principal Investigator:

Richard Foltin, Ph.D.

Columbia University

More Information

No publications provided

Study ID Numbers:	NIDA-06234-4, R01-06234-4
Study First Received:	September 20, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00000215 History of Changes
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Cocaine-Related Disorders
Neurotransmitter Agents
Dopamine
Mental Disorders
Substance-Related Disorders

Disorders of Environmental Origin
Dopamine Agents
Dopamine Agonists
Cocaine
Pergolide

Additional relevant MeSH terms:

Cocaine-Related Disorders
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Mental Disorders
Physiological Effects of Drugs
Substance-Related Disorders

Disorders of Environmental Origin
Dopamine Agents
Dopamine Agonists
Pergolide
Pharmacologic Actions

ClinicalTrials.gov processed this record on July 02, 2009