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IV Cocaine Abuse: A Laboratory Model - 2

This study has been completed.
Sponsor:
Collaborators:
National Institute on Drug Abuse (NIDA)
Columbia University
Information provided by (Responsible Party):
New York State Psychiatric Institute
ClinicalTrials.gov Identifier:
NCT00000213
First received: September 20, 1999
Last updated: December 11, 2012
Last verified: December 2012
History of Changes
  Purpose

The purpose of this study is to evaluate the effects of fluoxetine maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.


Condition Intervention Phase
Cocaine-Related Disorders
 Drug: Fluoxetine
 Phase 2

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: IV Cocaine Abuse: A Laboratory Model

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by New York State Psychiatric Institute:

Primary Outcome Measures:
  • Direct cocaine effects
  • Interaction of cocaine/fluox. on cardio measures
  • Interaction of cocaine/fluox. on coc's subjective
  • Effects of fluoxetine on cocaine craving
  • Drug use during outpatient fluoxetine maintenance

Estimated Enrollment: 0
Study Start Date: April 1990
Study Completion Date: April 1991
Primary Completion Date: April 1991 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Please contact site for information.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000213

Locations
United States, New York
Columbia University
New York, New York, United States, 10023
Sponsors and Collaborators
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)
Columbia University
Investigators
Principal Investigator: Richard Foltin, Ph.D. Columbia University
  More Information

No publications provided

Responsible Party: New York State Psychiatric Institute
ClinicalTrials.gov Identifier: NCT00000213     History of Changes
Other Study ID Numbers: NIDA-06234-2, R01DA006234, R01-06234-2
Study First Received: September 20, 1999
Last Updated: December 11, 2012
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Mental Disorders
Fluoxetine
Serotonin Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
 Pharmacologic Actions
Serotonin Agents
Physiological Effects of Drugs
Antidepressive Agents, Second-Generation
Antidepressive Agents
Psychotropic Drugs
Central Nervous System Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on May 21, 2013