Neurobiology of Opioid Dependence: 1 - 1 - Full Text View

Neurobiology of Opioid Dependence: 1 - 1

This study has been completed.

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) Yale University
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000192

Purpose

The purpose of this study is to evaluate the effects of lamotrigine on naloxone-precipitated opiate withdrawal.

Condition	Intervention	Phase
Opioid-Related Disorders	Drug: Lamotrigine	Phase II

Drug Information available for:

Lamotrigine

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Double-Blind, Placebo Control

Official Title:	Neurobiology of Opioid Dependence: 1

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Behavioral, subjective, measures of naloxone-precipitated opiate withdrawal
Phsyiological, neuroendocrine measures of naloxone-precipitated opiate withdrawal

Estimated Enrollment:	0
Study Start Date:	January 1995

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000192

Locations


United States, Connecticut
	VA Connecticut Healthcare System
	New Haven, Connecticut, United States, 06519

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Yale University

Investigators


Principal Investigator:	Marc I Rosen, M.D.	VA Connecticut Healthcare System

More Information

Publications:

Rosen, MI et al; Drug and Alcohol Dependence, 1998: 52:p173-176. CPDD, 1996 Meeting.

Study ID Numbers:	NIDA-00191-1, K20-00191-1
First Received:	September 20, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00000192
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Mental Disorders

Lamotrigine

Substance-Related Disorders

Disorders of Environmental Origin

Opioid-Related Disorders

Additional relevant MeSH terms:

Membrane Transport Modulators

Molecular Mechanisms of Pharmacological Action

Therapeutic Uses

Calcium Channel Blockers

Cardiovascular Agents

Central Nervous System Agents

Anticonvulsants

Pharmacologic Actions

ClinicalTrials.gov processed this record on December 03, 2008