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Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women

This study has been completed.

Sponsored by: National Center for Research Resources (NCRR)
Information provided by: National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier: NCT00000108
  Purpose

The purpose of this research is to find out whether training at different exercise intensities reduces the risk of developing cardiovascular disease (CVD) to a different extent. Heart attacks and stroke are the leading cause of death in older women. Reduced variability of the heart rate and increased dips and swings in blood pressure are risks factors that predict the chance of developing CVD as are increased levels of clotting protein fibrinogen and plasminogen activator inhibitor 1, and high levels of LDL-cholesterol (>160mg/dl). We will be measuring all of these risk factors and any changes in your body fat level before you start training and after 15 and 30 weeks of training in the form of walking. At the present time the effects of exercise intensity on these factors are not well understood. This study will add to the basic understanding of these issues and allow us to recommend to postmenopausal women optimal exercise intensities to lose body fat and reduce the risk of developing CVD.


Condition Intervention
Cardiovascular Diseases
Coronary Disease
Behavioral: Exercise

MedlinePlus related topics:   Exercise and Physical Fitness   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Prevention, Randomized, Parallel Assignment
  Eligibility
Ages Eligible for Study:   50 Years to 65 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion Criteria:

  • Postmenopausal and preferably on hormone replacement therapy
  • In good general health
  • Have a body mass index (BMI, weight in kg/height in m2) of between 25 and 40
  • Exercise less than 20 min/day two days a week
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000108

Locations
United States, Michigan
3060G Central Campus Recreation Bldg 401 Washtenaw Ave.    
      Ann Arbor, Michigan, United States, 48109-2214

Sponsors and Collaborators
  More Information


Study ID Numbers:   NCRR-M01RR00042-1647, M01RR00042
First Received:   January 18, 2000
Last Updated:   June 23, 2005
ClinicalTrials.gov Identifier:   NCT00000108
Health Authority:   United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):
exercise  

Study placed in the following topic categories:
Coronary Disease
Heart Diseases
Myocardial Ischemia
Vascular Diseases
Ischemia

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on October 10, 2008




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