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Found 22 studies with search of: Von Hippel-Lindau Disease (VHL)
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Rank Status Study
1 Recruiting Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease
Conditions: Von Hippel-Lindau Disease;   Hemangioblastoma;   Renal Cell Carcinoma;   Pheochromocytoma;   Pancreatic Neuroendocrine Tumor
Intervention: Other: 89Zr bevacizumab PET scan
2 Completed 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Von Hippel-Lindau Disease and Kidney Cancer
Conditions: Kidney Cancer;   Von Hippel-Lindau Syndrome
Intervention: Drug: tanespimycin
3 Recruiting A Pilot Study of Bevacizumab (Avastin) in Patients With Unresectable or Recurrent Hemangioblastoma From Von-Hippel-Lindau Disease
Conditions: Hemangioblastomas;   Von Hippel Lindau Disease
Intervention: Drug: Avastin
4 Completed Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors
Conditions: Deafness;   Kidney Diseases;   Kidney Neoplasms;   Neoplasms;   Retinal Diseases
Intervention:
5 Completed Ranibizumab Injections to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: Ranibizumab
6 Completed EYE001 to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome
Condition: Hippel-Lindau Disease
Intervention: Drug: EYE001
7 Recruiting Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: SU011248
8 Recruiting Vandetanib in Treating Patients With Von Hippel-Lindau Syndrome and Kidney Tumors
Conditions: Kidney Cancer;   Von Hippel-Lindau Syndrome
Interventions: Drug: vandetanib;   Genetic: gene expression analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: flow cytometry;   Other: laboratory biomarker analysis
9 Completed Treatment of Von Hippel-Lindau (VHL)-Related Hemangioblastoma With PTK787/ZK 222584
Conditions: Von Hippel-Lindau Disease;   CNS Hemangioblastoma;   Retinal Hemangioblastoma
Intervention: Drug: PTK787/ZK 222584
10 Recruiting Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau Syndrome
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: Sunitinib Malate
11 Completed Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome
Conditions: Kidney Cancer;   Von Hippel-Lindau Syndrome
Intervention: Genetic: mutation analysis
12 Active, not recruiting Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease
Conditions: Hemangioblastoma;   Hippel Lindau Disease
Intervention:
13 Active, not recruiting Diagnostic and Genetic Study to Identify Pancreatic Lesions in Patients With Von Hippel-Lindau Syndrome
Conditions: Neuroendocrine Carcinoma;   Pancreatic Cancer;   Von Hippel-Lindau Syndrome
Interventions: Genetic: comparative genomic hybridization;   Genetic: microarray analysis;   Genetic: mutation analysis;   Genetic: proteomic profiling;   Procedure: computed tomography;   Procedure: magnetic resonance imaging;   Procedure: ultrasound imaging;   Radiation: fludeoxyglucose F 18;   Radiation: fluorodopamine F 18
14 Active, not recruiting Genetic Study of Patients With Von Hippel-Lindau Syndrome
Condition: Kidney Cancer
Intervention: Genetic: polymorphic microsatellite marker analysis
15 Recruiting Genetic Study of Patients With Inherited Urologic Malignancies
Conditions: Birt Hogg Dube Syndrome;   Kidney Cancer;   Multiple Endocrine Neoplasia;   Von Hippel-Lindau Syndrome
Interventions: Genetic: DNA ploidy analysis;   Genetic: genetic linkage analysis;   Genetic: mutation analysis;   Genetic: polymorphic microsatellite marker analysis;   Other: medical chart review
16 Completed Tumor Angiogenesis in Patients With Endocrine Tumors
Conditions: Adrenocortical Carcinoma;   Head and Neck Cancer;   Islet Cell Tumor;   Multiple Endocrine Neoplasia;   Neoplastic Syndrome;   Neuroblastoma;   Pheochromocytoma;   Von Hippel-Lindau Syndrome
Interventions: Genetic: DNA methylation analysis;   Genetic: in situ hybridization;   Genetic: microarray analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Procedure: biopsy
17 Recruiting Melphalan and Mannitol in Treating Patients With Central Nervous System Cancer
Conditions: Brain and Central Nervous System Tumors;   Chordoma;   Lymphoma;   Metastatic Cancer;   Von Hippel-Lindau Syndrome
Interventions: Drug: mannitol;   Drug: melphalan
18 Recruiting Metabolic Mapping to Measure Retinal Metabolism
Conditions: Macular Degeneration;   Diabetic Retinopathy;   Hippel-Landau Disease;   Retina[ME];   Mitochondria
Intervention: Procedure: Feasibility Study - Imaging System
19 Active, not recruiting Vaccine Therapy in Treating Patients With Metastatic Kidney Cancer
Condition: Kidney Cancer
Interventions: Biological: aldesleukin;   Biological: incomplete Freund's adjuvant;   Biological: sargramostim;   Biological: von Hippel-Lindau peptide vaccine
20 Recruiting Diagnosis of Pheochromocytoma
Condition: Pheochromocytoma
Intervention:

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