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27 studies found for:    Von Hippel-Lindau Disease (VHL)

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Rank Status Study
1 Completed Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease
Conditions: Von Hippel-Lindau Disease;   Hemangioblastoma;   Renal Cell Carcinoma;   Pheochromocytoma;   Pancreatic Neuroendocrine Tumor
Intervention: Other: 89Zr bevacizumab PET scan
2 Completed
Has Results 		17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease
Conditions: Hippel-Lindau Disease;   Kidney Cancer
Interventions: Drug: 17 allylamino-17-demethoxygeldanamycin;   Drug: 18 FDG (Fludeoxyglucose 18F);   Drug: [15-O] H2O;   Drug: EPL diluent
3 Completed Treatment of Von Hippel-Lindau (VHL)-Related Hemangioblastoma With PTK787/ZK 222584
Conditions: Von Hippel-Lindau Disease;   Central Nervous System Capillary Hemangioblastoma;   Retinal Capillary Hemangioblastoma
Intervention: Drug: PTK787/ZK 222584
4 Terminated
Has Results 		Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow
Conditions: Von Hippel-Lindau Syndrome;   Renal Cell Carcinoma;   Hemangioblastoma
Intervention: Drug: SU011248
5 Terminated Bevacizumab (Avastin) in Unresectable/Recurrent Hemangioblastoma From Von-Hippel-Lindau Disease
Conditions: Hemangioblastomas;   Von Hippel Lindau Disease
Intervention: Drug: Avastin
6 Terminated
Has Results 		Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau Syndrome
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: Sunitinib Malate
7 Completed Ranibizumab Injections to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: Ranibizumab
8 Completed EYE001 to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome
Condition: Hippel-Lindau Disease
Intervention: Drug: EYE001
9 Completed Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome
Conditions: Kidney Cancer;   Von Hippel-lindau Syndrome
Intervention: Genetic: mutation analysis
10 Completed Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors
Conditions: Deafness;   Kidney Diseases;   Kidney Neoplasms;   Neoplasms;   Retinal Diseases
Intervention:
11 Completed Study of Sunitinib in Patients With Von Hippel-Lindau (VHL) Disease
Condition: Von Hippel-Lindau Disease
Intervention: Drug: Sunitinib
12 Active, not recruiting Von Hippel-Lindau Disease Genetic Epidemiology Study
Condition: Hippel Lindau Disease
Intervention:
13 Active, not recruiting Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease
Conditions: Hemangioblastoma;   Hippel Lindau Disease
Intervention:
14 Recruiting Pazopanib in Von Hippel-Lindau (VHL) Syndrome
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: Pazopanib
15 Recruiting Phase II Study of Vandetanib in Individuals With Kidney Cancer
Conditions: Renal Cancer;   Von Hippel Lindau
Intervention: Drug: ZACTIMA (Vandetanib) (ZD6474)
16 Recruiting TKI 258 in Von Hippel-Lindau Syndrome (VHL)
Condition: Von Hippel-Lindau Syndrome
Intervention: Drug: Dovitinib
17 Recruiting Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease
Condition: Pancreatic Lesions
Intervention:
18 Recruiting Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders
Conditions: Hemangioblastoma;   Hereditary Neoplastic Syndrome;   Hippel Lindau Disease;   Neoplasm;   Renal Cell Carcinoma
Intervention:
19 Completed Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy
Conditions: Coats' Disease;   Idiopathic Retinal Telangiectasia;   Retinal Angiomatous Proliferation;   Polypoidal Choroidal Vasculopathy;   Pseudoxanthoma Elasticum;   Pathological Myopia;   Multi-focal Choroiditis;   Rubeosis Iridis;   Von Hippel Lindau Disease;   BEST VITELLIFORM MACULAR DYSTROPHY, MULTIFOCAL (Disorder)
Intervention: Drug: ranibizumab injection (0.5 mg)
20 Completed
Has Results 		Vaccine Therapy With Tumor Specific Mutated VHL Peptides in Adult Cancer Patients With Renal Cell Carcinoma
Condition: Renal Cell Carcinoma
Interventions: Biological: incomplete Freund's adjuvant;   Biological: von Hippel-Lindau peptide vaccine
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† Indicates status has not been verified in more than two years