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Found 93 studies with search of: Primary Lateral Sclerosis
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Rank Status Study
1 Completed Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
Conditions: Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia;   Amyotrophic Lateral Sclerosis
Intervention:
2 Completed Brain Function in Primary Lateral Sclerosis
Condition: Motor Neuron Disease
Intervention:
3 Recruiting Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis
Condition: Cerebral Cortex Dysfunction
Intervention:
4 Recruiting Genetics of ALS: Identification of Genes With Roles in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS) and Amyotrophic Lateral Sclerosis (ALS) With Frontotemporal Dementia
Conditions: Amyotrophic Lateral Sclerosis;   Familial Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis With Frontotemporal Dementia;   Lou Gehrig's Disease;   Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention: Other: Genetic study of ALS families
5 Recruiting Collection of Blood Samples for DNA in Motor Neuron Disease
Condition: Motor Neuron Diseases
Intervention:
6 Completed Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
Conditions: Motor Neuron Disease;   Amyotrophic Lateral Sclerosis;   Primary Lateral Sclerosis;   Progressive Muscular Atrophy
Intervention: Biological: Levetiracetam
7 Recruiting Physiologic Studies of Spasticity
Conditions: Muscle Spasticity;   Healthy
Intervention:
8 Terminated Study to Investigate the Safety and Efficacy of Lithium in Volunteers With ALS
Conditions: Amyotrophic Lateral Sclerosis;   ALS
Interventions: Drug: Lithium;   Drug: Riluzole;   Drug: placebo
9 Active, not recruiting Study of Pioglitazone in Patients With Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: pioglitazone;   Drug: placebo
10 Recruiting Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: tauroursodeoxycholic acid (TUDCA);   Drug: Placebo
11 Recruiting Phase II/III Randomized, Placebo-Controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
Conditions: Hereditary ALS;   Familial ALS;   Familial Form of Amyotrophic Lateral Sclerosis (fALS);   SOD1 Positive ALS;   Inherited ALS
Intervention: Drug: Arimoclomol
12 Active, not recruiting Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)
Conditions: Amyotrophic Lateral Sclerosis;   Sialorrhea
Interventions: Drug: Botulinum toxin type B (Myobloc);   Procedure: Injection of salivary glands
13 Active, not recruiting Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS
Condition: Pseudobulbar Affect (PBA)
Intervention: Drug: AVP-923
14 Active, not recruiting Growth Hormone in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Growth Hormone (Somatropin);   Drug: Placebo
15 Recruiting Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Olesoxime;   Drug: Placebo Comparator
16 Recruiting Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   Chronic Respiratory Failure
Interventions: Device: Non invasive ventilation delivered with one of the ventilator specifically designed for NIV and given to the patient by the home care providers;   Device: Non invasive ventilation
17 Active, not recruiting Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: KNS-760704
18 Terminated The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Behavioral: Intensive Controlled Exercise
19 Completed Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III
Condition: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Drug: MCI-186;   Drug: Placebo of MCI-186
20 Completed Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: Creatinine

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