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Found 92 studies with search of: Diffuse Sclerosis
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Rank Status Study
1 Completed Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis
Conditions: Systemic Scleroderma;   Skin Fibrosis;   Hand Functionality
Intervention: Drug: Bosentan (Tracleer)
2 Active, not recruiting Gleevec in the Treatment of Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Drug: Imatinib Mesylate
3 Active, not recruiting Stimulatory Autoantibodies to the Platelet-Derived Growth Factor Receptor (PDGFR) and Phosphorylation of the Platelet-Derived Growth Factor Receptor (PDGFR) in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
4 Recruiting Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Drug: treprostinil diethanolamine
5 Completed Stem Cell Transplant to Treat Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Cyclophosphamide;   Drug: Mesna;   Drug: G-CSF;   Procedure: Leukopheresis;   Procedure: Total Body Irradiation
6 Recruiting AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Hyperimmune caprine serum;   Drug: Albumin
7 Recruiting A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis
Conditions: Alveolitis;   Systemic Sclerosis
Intervention: Drug: Gleevec
8 Active, not recruiting Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis, Scleroderma
Intervention: Drug: STI571
9 Completed Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma
Condition: Systemic Sclerosis
Intervention: Drug: Relaxin
10 Completed Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Human Anti-Transforming Growth Factor Beta-1 Monoclonal Antibody
11 Not yet recruiting Small Intestinal Mucosal Abnormalities in Systemic Sclerosis Using Capsule Endoscopy
Condition: Systemic Sclerosis
Intervention: Other: Endoscopic capsule
12 Completed The Effect of Physical Therapy on Raynaud`s Phenomenon Secondary to Systemic Sclerosis
Conditions: Raynaud's Phenomenon;   Systemic Sclerosis
Interventions: Other: Biofeedback;   Other: Deep oscillation
13 Active, not recruiting Angiogenic/Angiostatic Mediators in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
14 Recruiting Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
15 Recruiting Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan
Conditions: Systemic Sclerosis;   Shortness of Breath;   Pulmonary Hypertension
Intervention: Drug: Ambrisentan
16 Recruiting Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Various Treatments
Condition: Systemic Sclerosis
Intervention:
17 Recruiting Effectiveness of UVA1-irradiation in the Treatment of Early Skin Fibrosis in Patients Suffering From Systemic Sclerosis
Conditions: Systemic Scleroderma;   Systemic Sclerosis
Interventions: Radiation: UVA1;   Other: UVA1
18 Recruiting Efficacy and Safety Study of p144 to Treat Skin Fibrosis in Systemic Sclerosis
Condition: Skin Fibrosis
Interventions: Drug: p144;   Drug: placebo
19 Terminated QAX576 in Patients With Pulmonary Fibrosis Secondary to Systemic Sclerosis
Condition: Pulmonary Fibrosis Secondary to Systemic Sclerosis
Interventions: Drug: QAX576;   Drug: Placebo
20 Terminated Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
Conditions: Scleroderma;   Systemic Sclerosis
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Thymoglobulin;   Procedure: Leukapheresis;   Procedure: Self bone marrow transplant

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