3 studies found for:    19726763 [PUBMED-IDS]
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Rank Status Study
1 Recruiting Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway
Conditions: Histologically Confirmed Medulloblastoma;   Activation of the Sonic Hedgehog (SHH) Pathway
Interventions: Drug: vismodegib;   Drug: Temozolomide
2 Recruiting Study Evaluating the Efficacy of Oral Vismodegib in Various Histologic Subtypes
Condition: Basal Cell Carcinoma
Intervention: Drug: vismodegib (150 mg PO daily)
3 Completed GDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: Hedgehog antagonist GDC-0449;   Genetic: gene expression analysis;   Genetic: protein analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: liquid chromatography;   Other: mass spectrometry;   Other: pharmacological study

Indicates status has not been verified in more than two years