10360 studies found for:    NCI
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Rank Status Study
1 Completed
Has Results
S0338, Imatinib Mesylate and Capecitabine in Treating Women With Progressive Stage IV Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Capecitabine;   Drug: Imatinib mesylate
2 Completed Irofulven in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Peritoneal Cancer
Conditions: Fallopian Tube Cancer;   Ovarian Cancer;   Primary Peritoneal Cavity Cancer
Intervention: Drug: irofulven
3 Completed Diindolylmethane in Healthy Volunteers
Condition: Healthy, no Evidence of Disease
Intervention: Drug: oral microencapsulated diindolylmethane
4 Recruiting Paclitaxel, Cisplatin, and Veliparib in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
Conditions: Cervical Adenocarcinoma;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma;   Recurrent Cervical Cancer;   Stage IVB Cervical Cancer
Interventions: Drug: veliparib;   Other: immunohistochemistry staining method;   Other: diagnostic laboratory biomarker analysis;   Drug: cisplatin;   Drug: paclitaxel
5 Recruiting Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma
Conditions: Adult Alveolar Soft-part Sarcoma;   Adult Angiosarcoma;   Adult Desmoplastic Small Round Cell Tumor;   Adult Epithelioid Hemangioendothelioma;   Adult Epithelioid Sarcoma;   Adult Extraskeletal Chondrosarcoma;   Adult Extraskeletal Osteosarcoma;   Adult Fibrosarcoma;   Adult Leiomyosarcoma;   Adult Liposarcoma;   Adult Malignant Fibrous Histiocytoma;   Adult Malignant Mesenchymoma;   Adult Neurofibrosarcoma;   Adult Rhabdomyosarcoma;   Adult Synovial Sarcoma;   Chondrosarcoma;   Clear Cell Sarcoma of the Kidney;   Conjunctival Kaposi Sarcoma;   Dermatofibrosarcoma Protuberans;   Gastrointestinal Stromal Tumor;   Metastatic Adult Malignant Fibrous Histiocytoma of Bone;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Osteosarcoma;   Ovarian Sarcoma;   Recurrent Adult Malignant Fibrous Histiocytoma of Bone;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Kaposi Sarcoma;   Recurrent Osteosarcoma;   Recurrent Uterine Sarcoma;   Small Intestine Leiomyosarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage III Uterine Sarcoma;   Stage IV Adult Soft Tissue Sarcoma;   Stage IV Uterine Sarcoma
Interventions: Drug: vismodegib;   Drug: gamma-secretase/Notch signalling pathway inhibitor RO4929097;   Other: laboratory biomarker analysis;   Other: pharmacological study
6 Completed Flavopiridol, Gemcitabine, and Irinotecan in Treating Patients With Unresectable or Metastatic Solid Tumors
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: alvocidib;   Drug: gemcitabine hydrochloride;   Drug: irinotecan hydrochloride
7 Completed 3-AP in Treating Patients With Advanced or Metastatic Solid Tumors
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: triapine;   Other: pharmacological study;   Procedure: laboratory biomarker analysis
8 Recruiting Vorinostat in Treating Patients With Metastatic Melanoma of the Eye
Conditions: Metastatic Intraocular Melanoma;   Recurrent Intraocular Melanoma
Interventions: Drug: vorinostat;   Other: laboratory biomarker analysis
9 Terminated Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer
Conditions: Ovarian Dysgerminoma;   Recurrent Malignant Testicular Germ Cell Tumor;   Recurrent Ovarian Germ Cell Tumor;   Stage II Malignant Testicular Germ Cell Tumor;   Stage II Ovarian Germ Cell Tumor;   Stage III Malignant Testicular Germ Cell Tumor;   Stage III Ovarian Germ Cell Tumor;   Testicular Seminoma
Interventions: Drug: imatinib mesylate;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis
10 Completed Lapatinib Ditosylate in Treating Patients With Ductal Breast Carcinoma In Situ
Conditions: Ductal Breast Carcinoma in Situ;   HER2-positive Breast Cancer
Interventions: Drug: lapatinib ditosylate;   Other: placebo;   Other: laboratory biomarker analysis
11 Completed Surgery With or Without Chemotherapy in Treating Patients With Stage I Non-small Cell Lung Cancer
Conditions: Adenocarcinoma of the Lung;   Adenosquamous Cell Lung Cancer;   Bronchoalveolar Cell Lung Cancer;   Large Cell Lung Cancer;   Squamous Cell Lung Cancer;   Stage IB Non-small Cell Lung Cancer
Interventions: Drug: paclitaxel;   Drug: carboplatin;   Procedure: therapeutic conventional surgery
12 Completed
Has Results
Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By Surgery
Conditions: Adenocarcinoma of the Gastroesophageal Junction;   Diffuse Adenocarcinoma of the Stomach;   Intestinal Adenocarcinoma of the Stomach;   Mixed Adenocarcinoma of the Stomach;   Recurrent Gastric Cancer;   Stage IIIA Gastric Cancer;   Stage IIIB Gastric Cancer;   Stage IIIC Gastric Cancer;   Stage IV Gastric Cancer
Interventions: Drug: alvocidib;   Drug: irinotecan hydrochloride;   Other: laboratory biomarker analysis
13 Completed Neoadjuvant Tipifarnib, Docetaxel, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIA or Stage IIIB Breast Cancer
Conditions: Inflammatory Breast Cancer;   Male Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: tipifarnib;   Drug: capecitabine;   Drug: docetaxel;   Other: laboratory biomarker analysis;   Other: pharmacological study
14 Completed
Has Results
Bortezomib in Treating Patients With Stage IIIB or Stage IV Lung Cancer
Conditions: Adenocarcinoma of the Lung;   Bronchoalveolar Cell Lung Cancer;   Non-small Cell Lung Cancer;   Recurrent Non-small Cell Lung Cancer;   Stage IIIB Non-small Cell Lung Cancer;   Stage IV Non-small Cell Lung Cancer
Intervention: Drug: bortezomib
15 Completed Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer
Condition: Stage IV Pancreatic Cancer
Interventions: Drug: sorafenib tosylate;   Drug: gemcitabine hydrochloride;   Other: laboratory biomarker analysis
16 Active, not recruiting Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Conditions: Adult Acute Megakaryoblastic Leukemia (M7);   Adult Acute Minimally Differentiated Myeloid Leukemia (M0);   Adult Acute Monoblastic Leukemia (M5a);   Adult Acute Monocytic Leukemia (M5b);   Adult Acute Myeloblastic Leukemia With Maturation (M2);   Adult Acute Myeloblastic Leukemia Without Maturation (M1);   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Adult Acute Myelomonocytic Leukemia (M4);   Adult Erythroleukemia (M6a);   Adult Pure Erythroid Leukemia (M6b);   Recurrent Adult Acute Myeloid Leukemia
Interventions: Drug: alvocidib;   Drug: mitoxantrone hydrochloride;   Drug: carboplatin;   Drug: cytarabine;   Drug: sirolimus;   Drug: etoposide;   Drug: topotecan hydrochloride;   Other: laboratory biomarker analysis
17 Not yet recruiting Viral Protein Production After Dexamethasone, Wild-Type Reovirus, and Carfilzomib in Treating Patients With Multiple Myeloma
Condition: Refractory Multiple Myeloma
Interventions: Drug: dexamethasone;   Biological: wild-type reovirus;   Drug: carfilzomib;   Other: laboratory biomarker analysis
18 Completed Lymphocyte-Depleting Nonmyeloablative Preparative Chemotherapy Followed By Autologous Lymphocyte Infusion, Peptide Vaccine Plus Montanide ISA-51, and Interleukin-2 in Treating Patients With Metastatic Melanoma
Condition: Melanoma (Skin)
Interventions: Biological: NY-ESO-1 peptide vaccine;   Biological: aldesleukin;   Biological: filgrastim;   Biological: incomplete Freund's adjuvant;   Biological: therapeutic autologous lymphocytes;   Drug: cyclophosphamide;   Drug: fludarabine phosphate
19 Completed
Has Results
Obatoclax Mesylate and Topotecan Hydrochloride in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer or Advanced Solid Tumors
Conditions: Recurrent Small Cell Lung Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: obatoclax mesylate;   Drug: topotecan hydrochloride;   Other: laboratory biomarker analysis
20 Completed Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors
Conditions: Adult Rhabdomyosarcoma;   Adult Synovial Sarcoma;   Childhood Hepatoblastoma;   Childhood Synovial Sarcoma;   Previously Treated Childhood Rhabdomyosarcoma;   Recurrent Adrenocortical Carcinoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Liver Cancer;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Neuroblastoma;   Recurrent Osteosarcoma;   Recurrent Retinoblastoma;   Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: Biological: cixutumumab;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years