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32 studies found for:    Islets of Langerhans Transplantation | Open Studies

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Rank Status Study
1 Recruiting Pancreatic Islet Cell Transplantation - A Novel Approach to Improve Islet Quality and Engraftment
Conditions: Islet Cell Transplantation;   Type 1 Diabetes
Intervention: Drug: Islet cell transplantation
2 Recruiting Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Islets of Langerhans transplantation
3 Recruiting A Comparison of Islet Cell Transplantation With Medical Therapy for the Treatment of Diabetic Eye Disease
Conditions: Diabetic Retinopathy;   Diabetic Macular Edema
Interventions: Procedure: islet cell transplant;   Other: Medical therapy
4 Recruiting A Phase I/II Study of the Safety and Efficacy of Sernova's Cell PouchTM for Therapeutic Islet Transplantation
Condition: Type I Diabetes
Intervention: Device: Sernova Cell Pouch
5 Recruiting Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet Transplantation
Condition: Islet Transplantation in Diabetes Mellitus Type 1,
Interventions: Drug: Reparixin;   Drug: Placebo
6 Not yet recruiting A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell Transplantation
Conditions: Diabetes Mellitus, Type 1;   Islet Transplantation
Intervention: Other: Strict glucose control
7 Recruiting Islet Cell Transplantation in Patients With Type I Diabetes With Previous Kidney Transplantation
Conditions: Type 1 Diabetes;   Organ Transplantation;   Immunosuppression
Intervention: Procedure: islet transplantation
8 Recruiting Bone Marrow vs Liver as Site for Islet Transplantation
Condition: Type 1 Diabetes
Intervention: Biological: Human pancreatic islet transplantation
9 Unknown † Effect of Sitagliptin on Graft Function Following Islet Transplantation
Condition: Islet Transplantation
Intervention: Drug: sitagliptin
10 Recruiting Trial Comparing Metabolic Efficiency of Islet Graft to Intensive Insulin Therapy for Type 1 Diabetes's Treatment
Condition: Diabetes Mellitus, Type 1
Intervention: Procedure: human pancreatic islet transplantation
11 Not yet recruiting Heparinized Islets in Clinical Islet Transplantation
Condition: Islet Transplantation
Intervention: Procedure: Transplantation of islets with heparin coating
12 Recruiting Islet Transplantation in Type 1 Diabetic Kidney Allograft
Condition: Diabetes Mellitus, Type 1
Interventions: Biological: Allogenic islet cells (human, U. Chicago);   Procedure: Intraportal infusion of islet cells
13 Recruiting Islet Transplantation in Patients With "Brittle" Type I Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Biological: Allogenic islet cells (human, U. Chicago);   Procedure: Intraportal infusion of islet cells
14 Recruiting Caspase Inhibition in Islet Transplantation
Condition: Diabetes
Intervention: Drug: IDN-6556
15 Unknown † Islet of Langerhans Graft Monitoring by Magnetic Resonance Imaging
Condition: Type 1 Diabetes Mellitus
Interventions: Drug: ferucarbotran (iron-based MRI contrast agent);   Procedure: Islet transplantation;   Procedure: Magnetic resonance imaging
16 Recruiting Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation
Condition: Diabetes Mellitus, Type I
Interventions: Drug: Low Molecular Weight Sulfated Dextran (LMW-SD);   Drug: Heparin;   Drug: CellCept® (Mycophenolate mofetil) OR Rapamune® (Sirolimus);   Drug: Prograf® (Tacrolimus) OR Cyclosporine;   Drug: Thymoglobulin® (Anti-thymocyte Globulin) - at first transplant;   Drug: Simulect® (Basiliximab) - at 2nd or 3rd transplant;   Drug: Klexane® (Enoxaparinsodium);   Drug: Trombyl® or Albyl-E® (Acetylsalicylicacid- ASA);   Drug: Enbrel® (Etanercept)
17 Recruiting Efficacy of Islet After Kidney Transplantation
Condition: Type 1 Diabetes Mellitus
Intervention: Biological: Islet transplant
18 Unknown † Does Islet Transplantation Eliminate Hypoglycemia?
Condition: Diabetes Mellitus
Intervention: Procedure: Pancreatic Islet Transplantation
19 Recruiting Cotransplantation of Islet and Mesenchymal Stem Cell in Type 1 Diabetic Patients
Condition: Type 1 Diabetes Mellitus
Intervention: Biological: cotransplantation of islet and mesenchymal stem cell
20 Recruiting Extending Indication for Islet Autotransplantation in Pancreatic Surgery
Condition: Diabetes
Intervention:
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† Indicates status has not been verified in more than two years