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Found 52 studies with search of: Open Studies | "gene therapy"
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Rank Status Study
1 Not yet recruiting rAd-p53 Gene Therapy for Advanced Malignant Thyroid Tumors
Condition: Advanced Malignant Thyroid Tumors
Interventions: Drug: rAd-p53 gene;   Procedure: surgery;   Drug: p53 gene therapy;   Radiation: p53 gene therapy with radioactive iodine
2 Not yet recruiting rAd-p53 Gene Therapy for Advanced Oral and Maxillofacial Malignant Tumors
Condition: Advanced Oral and Maxillofacial Malignant Tumors
Interventions: Drug: p53 gene with surgery;   Procedure: surgery;   Drug: p53 with chemotherapy;   Drug: p53 gene therapy
3 Recruiting Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)
Condition: Muscular Dystrophies
Interventions: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- First cohort;   Genetic: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- Second cohort
4 Recruiting Gene Therapy With GX-12 in Combination With HAART for the HIV-1 Infected Patients
Condition: HIV Infections
Interventions: Genetic: GX-12;   Drug: HAART
5 Recruiting Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Conditions: Severe Combined Immunodeficiency;   Malignancy, Hematologic;   Neuroblastoma;   Neoplasm;   Mucopolysaccharidosis I
Intervention: Procedure: Venipuncture
6 Recruiting Phase III Randomized Trial of Suicide Gene Therapy and Prostate Cancer
Condition: Prostate Cancer
Interventions: Biological: Ad5-yCD/mutTKSR39rep-ADP;   Radiation: IMRT
7 Recruiting Safety Study of RPE65 Gene Therapy to Treat Leber Congenital Amaurosis
Condition: Retinal Degeneration
Intervention: Biological: tgAAG76 (rAAV 2/2.hRPE65p.hRPE65)
8 Not yet recruiting EndocardialVascularEndothelialGrowth Factor D(VEGF-D)Gene Therapy for the Treatment of Severe Coronary Heart Disease
Conditions: Angina Pectoris;   Myocardial Infarction
Intervention: Biological: VEGF-D gene transfer
9 Recruiting Adjuvant Adenovirus-Thymidine Kinase Enzyme (ADV-TK) Gene Therapy Improves Survival in Patients With Gliomas
Condition: Glioma
Intervention: Biological: ADV-TK
10 Not yet recruiting Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease
Condition: Pompe Disease
Intervention: Drug: rAAV1-CMV-GAA
11 Recruiting Retroviral Vector Mediated Globin Gene Transfer to Correct Sickle Cell Anemia or Thalassemia
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention: Genetic: Gene Therapy
12 Recruiting Gene Therapy and Radioactive Iodine in Treating Patients With Locally Recurrent Prostate Cancer That Did Not Respond to External-Beam Radiation Therapy
Condition: Prostate Cancer
Interventions: Biological: Ad5-CMV-NIS;   Drug: liothyronine sodium;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: laboratory biomarker analysis;   Radiation: iodine I 131
13 Recruiting Phase I Study Combining Suicide Gene Therapy With Chemoradiotherapy in the Treatment of Non-Metastatic Pancreatic Adenocarcinoma
Condition: Pancreatic Cancer
Intervention: Genetic: ad5-yCD/mutTKSR39rep-ADP
14 Recruiting Gene Therapy for Pleural Malignancies
Conditions: Pleural Mesothelioma;   Metastatic Pleural Effusions
Intervention: Gene Transfer: BG00001 (adenoviral-mediated interferon-beta)
15 Recruiting Gene Therapy for Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Intervention: Drug: Phagocyte Oxidase Subunit Transduced CD34 Hematopoietic Stem Cells
16 Recruiting Gene Therapy for Prostate Cancer That Returns After Radiation Therapy
Conditions: Prostatic Neoplasms;   Neoplasm Recurrence, Local
Intervention: Gene Transfer: Ad.hIL-12
17 Not yet recruiting Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia
Condition: Critical Limb Ischemia
Interventions: Genetic: VM202;   Other: Normal Saline
18 Not yet recruiting p53 Gene Therapy for Head and Neck Malignant Tumors in Advanced Stage
Condition: Malignant Tumors
Intervention: Drug: rAd-p53 gene
19 Recruiting A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer
Condition: Prostate Cancer
Intervention: Biological: Gene Directed Enzyme Prodrug Therapy, FP253/Fludarabine
20 Recruiting Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma
Conditions: Malignant Melanoma;   Neoplasm Metastasis
Intervention: Genetic: investigational drug INGN 241

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