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Found 55 studies with search of: Open Studies | Amyotrophic Lateral Sclerosis
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Rank Status Study
1 Recruiting Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis 1;   Acquired Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis
Intervention: Drug: Arimoclomol
2 Recruiting Genetics of ALS: Identification of Genes With Roles in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS) and Amyotrophic Lateral Sclerosis (ALS) With Frontotemporal Dementia
Conditions: Amyotrophic Lateral Sclerosis;   Familial Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis With Frontotemporal Dementia;   Lou Gehrig's Disease;   Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention: Other: Genetic study of ALS families
3 Recruiting High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Dietary Supplement: Oxepa;   Dietary Supplement: Jevity 1.5;   Dietary Supplement: Jevity 1.0
4 Unknown † Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   Chronic Respiratory Failure
Interventions: Device: Non invasive ventilation delivered with one of the ventilator specifically designed for NIV and given to the patient by the home care providers;   Device: Non invasive ventilation
5 Unknown † Effect of Lithium Carbonate in Patients With Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: lithium
6 Recruiting Study of Cognitive and Emotional Disorders in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Other: MRI + 18FDG-PET + neuropsychological assessments ; 18FDG performed especially for the research
7 Recruiting Safety and Efficacy Study of Autologous Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   ALS
Interventions: Biological: HYNR-CS inj;   Biological: Control group
8 Not yet recruiting Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation
Conditions: Amyotrophic Lateral Sclerosis;   Respiratory Insufficiency
Interventions: Device: phenique nerve stimulation NeurX™ (Synapse Biomedical);   Device: sham phrenic nerve stimulation
9 Recruiting Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
Conditions: Sialorrhea;   Amyotrophic Lateral Sclerosis
Interventions: Drug: Botox injection;   Drug: Placebo injection
10 Recruiting Noninvasive Examination of the Work of Breathing in Patients With Amyotrophic Lateral Sclerosis (ALS).
Conditions: Amyotrophic Lateral Sclerosis;   Cerebrospinal Fluid;   Neurodegenerative Disease;   Motor Neuron Disease
Intervention:
11 Unknown † Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: Cistanche Total Glycosides
12 Recruiting Clinical Trial on The Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (Extension CMN/ELA)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Procedure: Laminectomy and bone marrow stem cells transplantation;   Procedure: Intrathecal infusion of autologous bone marrow stem cells;   Procedure: Intrathecal infusion of placebo (saline solution).
13 Recruiting Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
Conditions: Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   PLS;   Motor Neuron Disease;   Lou Gehrigs Disease;   Familial Disease;   Amyotrophic Lateral Sclerosis, Sporadic
Intervention:
14 Recruiting Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Drug: MCI-186;   Drug: Placebo;   Drug: MCI-186 in open label phase
15 Recruiting A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention: Drug: E0302 (mecobalamin)
16 Unknown † Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
Conditions: ALS;   Amyotrophic Lateral Sclerosis
Intervention:
17 Unknown † Neuromuscular Transmission in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Procedure: Anconeus Muscle biopsy
18 Recruiting Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   Motor Neuron Disease
Intervention: Device: noninvasive positive pressure ventilation
19 Not yet recruiting Transcranial Direct Current Stimulation as a Novel Therapeutic Approach in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Other: transcranial direct current stimulation;   Other: Sham stimulation
20 Not yet recruiting The Clinical Trial on the Use of Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Procedure: stem cell transplantation

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